Patrick Hsu is the co-founder of Arc Institute, which is integrating AI models and biological research. Patrick’s problem is this: How can you use AI to make biological research more efficient – and ultimately to find cures for Alzheimer’s and other complex diseases?

Patrick Hsu is the co-founder of Arc Institute, which is integrating AI models and biological research. Patrick&rsquo;s problem is this: How can you use AI to make biological research more efficient &ndash; and ultimately to find cures for Alzheimer&rsquo;s and other complex diseases?

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with entrepreneurs and engineers tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with&nbsp;entrepreneurs and engineers&nbsp;tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.
iHeartMedia is the exclusive podcast partner of Pushkin Industries.

What's Your Problem?

Every week on What’s Your Problem, entrepreneurs and engineers talk about the future they’re trying to build – and the problems they have to solve to get there.

How do you take a drone delivery service you’ve built in Rwanda and make it work in North Carolina? How do you convince people to buy a house on the Internet? How do you sell thousands of dog ramps to weiner dogs all across America when a pandemic breaks the global supply chain? 

Hosted by former Planet Money host Jacob Goldstein, What’s Your Problem helps listeners understand the problems really smart people are trying to solve right now.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Can AI Help Solve Alzheimer’s?

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/7655c7db-9c85-424d-b590-b3e1011d39e0/transcript

Investors are pouring billions of dollars into nuclear fusion companies. The dream: transform human civilization (and power AI data centers) by providing cheap, abundant energy. But nobody’s figured out how to make it work yet.

What will it take to make fusion work at scale – and how will the world be different if it does? To answer this question, Jacob recently hosted a conversation at SXSW between Greg Piefer of SHINE Technologies, Melanie Windridge of Fusion Energy Insights, and Luke Ward of investment firm Baillie Gifford. 

In this episode, the guests explain: 
The incredible promise of fusion
What it will take to realize that promise
How the AI boom and the demand for power is shaping the fusion industry
Why having a ton of money flowing into the field is not necessarily a good thing

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn and X 
Listen to Jacob’s other show, Business History 
To listen to the show early and ad free, sign up for Pushkin+

Investors are pouring billions of dollars into nuclear fusion companies. The dream: transform human civilization (and power AI data centers) by providing cheap, abundant energy. But nobody&rsquo;s figured out how to make it work yet.
What will it take to make fusion work at scale &ndash; and how will the world be different if it does? To answer this question, Jacob recently hosted <a href="https://schedule.sxsw.com/events/PP1162254">a conversation at SXSW</a> between Greg Piefer of SHINE Technologies, Melanie Windridge of Fusion Energy Insights, and Luke Ward of investment firm Baillie Gifford.&nbsp;
In this episode, the guests explain:&nbsp;
<ul>
<li>The incredible promise of fusion</li>
<li>What it will take to realize that promise</li>
<li>How the AI boom and the demand for power is shaping the fusion industry</li>
<li>Why having a ton of money flowing into the field is not necessarily a good thing</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en">X</a> and <a href="https://www.instagram.com/jacobjulius/?hl=en">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all"> LinkedIn</a> and <a href="https://x.com/pushkinpods?lang=en">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167">Business History&nbsp;</a></li>
<li>To listen to the show early and ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin">Pushkin+</a></li>
</ul>

The Great Fusion Debate: How Far Away Are We Really?

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/52edf143-90d2-4081-8a53-b42700edf3b5/transcript

Mark Barrocas is the CEO of SharkNinja, a company that sells everything from vacuums, to blenders, to beauty products. Mark’s problem is this: How do you invent new products that people want to rave about on social media? 

In this episode, Mark explains: 
How SharkNinja finds product ideas
The tradeoffs at the heart of product development
How the Ninja Creami became a viral hit
Why some products fail and others succeed. 

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show early and ad free, sign up for Pushkin+

Mark Barrocas is the CEO of SharkNinja, a company that sells everything from vacuums, to blenders, to beauty products. Mark&rsquo;s problem is this: How do you invent new products that people want to rave about on social media?&nbsp;
In this episode, Mark explains:&nbsp;
<ul>
<li>How SharkNinja finds product ideas</li>
<li>The tradeoffs at the heart of product development</li>
<li>How the Ninja Creami became a viral hit</li>
<li>Why some products fail and others succeed.&nbsp;</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en">X</a> and <a href="https://www.instagram.com/jacobjulius/?hl=en">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167">Business History&nbsp;</a></li>
<li>To listen to the show early and ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin">Pushkin+</a></li>
</ul>

How SharkNinja Keeps Going Viral

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/d3349032-eab0-4472-81b4-b41f0165ab99/transcript

Michael Hufford is the co-founder and CEO of LyGenesis, a company working on a new treatment for end stage liver disease. Michael’s problem is this: How do grow a new liver inside the body of a sick patient?

In this episode, Michael explains: 
The liver's unique power of regeneration
The organ transplant crisis and how regeneration can help 
The science behind using lymph nodes to grow new organs
The status of LyGenesis’ human trials
The future of regenerative medicine 

Learn more:
Check out LyGenesis’ website

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show early and ad free, sign up for Pushkin+

Michael Hufford is the co-founder and CEO of LyGenesis, a company working on a new treatment for end stage liver disease. Michael&rsquo;s problem is this: How do grow a new liver inside the body of a sick patient?
In this episode, Michael explains:&nbsp;
<ul>
<li>The liver's unique power of regeneration</li>
<li>The organ transplant crisis and how regeneration can help&nbsp;</li>
<li>The science behind using lymph nodes to grow new organs</li>
<li>The status of LyGenesis&rsquo; human trials</li>
<li>The future of regenerative medicine&nbsp;</li>
</ul>
Learn more:
<ul>
<li>Check out LyGenesis&rsquo; <a href="https://www.lygenesis.com/">website</a></li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en">X</a> and <a href="https://www.instagram.com/jacobjulius/?hl=en">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167">Business History&nbsp;</a></li>
<li>To listen to the show early and ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin">Pushkin+</a></li>
</ul>

Growing New Livers to Save Lives

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/27e74a34-c4d3-4481-8eba-b40c00f3b4cf/transcript

Can AI Help Solve Alzheimer’s?

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