Michael Hufford is the co-founder and CEO of LyGenesis, a company working on a new treatment for end stage liver disease. Michael’s problem is this: How do grow a new liver inside the body of a sick patient?

In this episode, Michael explains: 
The liver's unique power of regeneration
The organ transplant crisis and how regeneration can help 
The science behind using lymph nodes to grow new organs
The status of LyGenesis’ human trials
The future of regenerative medicine 

Learn more:
Check out LyGenesis’ website

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show early and ad free, sign up for Pushkin+

Michael Hufford is the co-founder and CEO of LyGenesis, a company working on a new treatment for end stage liver disease. Michael&rsquo;s problem is this: How do grow a new liver inside the body of a sick patient?
In this episode, Michael explains:&nbsp;
<ul>
<li>The liver's unique power of regeneration</li>
<li>The organ transplant crisis and how regeneration can help&nbsp;</li>
<li>The science behind using lymph nodes to grow new organs</li>
<li>The status of LyGenesis&rsquo; human trials</li>
<li>The future of regenerative medicine&nbsp;</li>
</ul>
Learn more:
<ul>
<li>Check out LyGenesis&rsquo; <a href="https://www.lygenesis.com/">website</a></li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/">Instagram</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167">Business History&nbsp;</a></li>
<li>To listen to the show early and ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin">Pushkin+</a></li>
</ul>

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with entrepreneurs and engineers tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with&nbsp;entrepreneurs and engineers&nbsp;tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.
iHeartMedia is the exclusive podcast partner of Pushkin Industries.

What's Your Problem?

Every week on What’s Your Problem, entrepreneurs and engineers talk about the future they’re trying to build – and the problems they have to solve to get there.

How do you take a drone delivery service you’ve built in Rwanda and make it work in North Carolina? How do you convince people to buy a house on the Internet? How do you sell thousands of dog ramps to weiner dogs all across America when a pandemic breaks the global supply chain? 

Hosted by former Planet Money host Jacob Goldstein, What’s Your Problem helps listeners understand the problems really smart people are trying to solve right now.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Growing New Livers to Save Lives

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/27e74a34-c4d3-4481-8eba-b40c00f3b4cf/transcript

On this bonus episode of What’s Your Problem, Jacob talks to Christine Chase, a Vice President, Financial Consultant at Fidelity Investments. Christine’s problem is this: How do you help clients build a plan to achieve their financial goals? Today’s show is sponsored by Fidelity Investments.

On this bonus episode of What&rsquo;s Your Problem, Jacob talks to Christine Chase, a Vice President, Financial Consultant at Fidelity Investments. Christine&rsquo;s problem is this: How do you help clients build a plan to achieve their financial goals? Today&rsquo;s show is sponsored by Fidelity Investments.

Bonus: Planning for Your Financial Future

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/f7ca05fb-7bd0-4e1c-8583-b4c00155ba68/transcript

The fish we eat usually die slowly, suffocating after they’re pulled out of the water. Saif Khawaja is the co-founder and CEO of a company called Shinkei. Saif's problem is this: Can he build a machine to efficiently kill fish in a way that is more humane?

In this episode, Saif explains: 
How he came to believe that our current fishing practices are inhumane 
How he adapted the Japanese technique of  ikijime for use at scale 
Why Shinkei’s process results in better texture and longer shelf life than commodity fish.
Why Shinkei is doing its own technology development, fish processing, and consumer branding. 

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show early and ad free, sign up for Pushkin+

The fish we eat usually die slowly, suffocating after they&rsquo;re pulled out of the water. Saif Khawaja is the co-founder and CEO of a company called Shinkei. Saif's problem is this: Can he build a machine to efficiently kill fish in a way that is more humane?
In this episode, Saif explains:&nbsp;
<ul>
<li>How he came to believe that our current fishing practices are inhumane&nbsp;</li>
<li>How he adapted the Japanese technique of  ikijime for use at scale&nbsp;</li>
<li>Why Shinkei&rsquo;s process results in better texture and longer shelf life than commodity fish.</li>
<li>Why Shinkei is doing its own technology development, fish processing, and consumer branding.&nbsp;</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/" data-airgap-id="11">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en" data-airgap-id="12">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/" data-airgap-id="13">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm" data-airgap-id="14">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/" data-airgap-id="15">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all" data-airgap-id="16"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en" data-airgap-id="17">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167" data-airgap-id="18">Business History&nbsp;</a></li>
<li>To listen to the show early and ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin" data-airgap-id="19">Pushkin+</a></li>
</ul>

Can a Robot Kill Fish Humanely?

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/31ea5f33-afa1-4a8d-a2c3-b4bb015f6b22/transcript

Catherine Nakalembe is an assistant professor at the University of Maryland and the head of the Africa program at NASA Harvest, which uses satellite images to track agriculture around the world. Catherine’s problem is this: How do you predict when a famine is coming – and how do you convince leaders to act in time?

In this episode, Catherine explains: 
How satellite data can predict crop failure months in advance
Why phots can convince decision-makers faster than maps or statistics
Why imaging systems developed for US farmland often don’t work in Africa
Why a half-page memo moves food trucks faster than a scientific paper

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show early and ad free, sign up for Pushkin+

Catherine Nakalembe is an assistant professor at the University of Maryland and the head of the Africa program at NASA Harvest, which uses satellite images to track agriculture around the world. Catherine&rsquo;s problem is this: How do you predict when a famine is coming &ndash; and how do you convince leaders to act in time?
In this episode, Catherine explains:&nbsp;
<ul>
<li>How satellite data can predict crop failure months in advance</li>
<li>Why phots can convince decision-makers faster than maps or statistics</li>
<li>Why imaging systems developed for US farmland often don&rsquo;t work in Africa</li>
<li>Why a half-page memo moves food trucks faster than a scientific paper</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/" data-airgap-id="11">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en" data-airgap-id="12">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/" data-airgap-id="13">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm" data-airgap-id="14">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/" data-airgap-id="15">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all" data-airgap-id="16"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en" data-airgap-id="17">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167" data-airgap-id="18">Business History&nbsp;</a></li>
<li>To listen to the show early and ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin" data-airgap-id="19">Pushkin+</a></li>
</ul>

Using Satellites to Prevent Famines

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/124e94fc-9c45-4d00-8c33-b4b3010a1293/transcript

Growing New Livers to Save Lives

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