Congress and Your Right To Be Anonymous 

Scientists have discovered a plant‑derived molecule called DHL‑11, isolated from Munronia henryi, that kills aggressive triple‑negative breast cancer cells by triggering a cascade of DNA damage, oxidative stress, and apoptosis.

The compound works by disrupting the cancer‑critical enzyme IMPDH2 in an unusual way — destabilizing it rather than simply blocking it — and showed strong effectiveness in both lab tests and patient‑derived tumor organoids. 

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Scientists have discovered a plant‑derived molecule called DHL‑11, isolated from Munronia henryi, that kills aggressive triple‑negative breast cancer cells by triggering a cascade of DNA damage, oxidative stress, and apoptosis.
The compound works by disrupting the cancer‑critical enzyme IMPDH2 in an unusual way &mdash; destabilizing it rather than simply blocking it &mdash; and showed strong effectiveness in both lab tests and patient‑derived tumor organoids.&nbsp;
<hr>
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Philip Teresi on KMJ
Weekdays 2-6 PM Pacific on News/Talk 580 AM &amp; 105.9 FM KMJ 
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Please Like, Comment and Follow 'Philip Teresi on KMJ' on all platforms:&nbsp; --- &nbsp; Philip Teresi on KMJ is available on the KMJNOW app, Apple Podcasts, Spotify, YouTube or wherever else you listen to podcasts. &nbsp; -- Philip Teresi on KMJ Weekdays 2-6 PM Pacific on News/Talk 580 AM &amp; 105.9 FM KMJ&nbsp; &nbsp;| Website &nbsp;| Facebook | Instagram | X | Podcast | Amazon |&nbsp; - Everything KMJ&nbsp; KMJNOW App | Podcasts | Facebook | X | Instagram &nbsp;
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Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ - Always Online at kmjnow.com 

Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ - Always Online at <a href="https://www.kmjnow.com/">kmjnow.com&nbsp;</a>

Philip Teresi

Ray Appleton began his radio career in Fresno in 1969. That career has taken him from Fresno to London and back. He has been a part of the KMJ team since 1987 and continues to share his thoughts and viewpoints with his very large and loyal audience weekdays from 11am-2pm on Central California's News Talk 580 and 105.9 KMJ!

Ray Appleton began his radio career in Fresno in 1969. That career has taken him from Fresno to London and back. He has been a part of the KMJ team since 1987 and continues to share his thoughts and viewpoints with his very large and loyal audience weekdays from 11am-2pm on Central California's News Talk 580 and 105.9 KMJ!

News Talk 580 & 105.9 KMJ Podcasts

Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ. Politically independent, socially awkward, and fashionably late.

Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ. Politically independent, socially awkward, and fashionably late.

Plant Compound vs Breast Cancer Cells & Your Right To Be Anonymous Online  

Mike & Dave dine on truffle honey glazed salmon served with a delightful '24 Willamette Valley Sauv Blanc.  The guys discuss visiting the Oregon wine country and Carson Kitchen in Vegas.  Mike explains the concept of "zebra striping" cocktails while deciding what to eat on their next space flight.

#SpaceTravel #ProjectHailMary #ArtemisII #NASA #LasVegas #OregonWine #LakeOswego #CarsonKitchen #KeelVodka https://keelvodka.com/ 

Mike &amp; Dave dine on truffle honey glazed salmon served with a delightful '24 Willamette Valley Sauv Blanc.&nbsp; The guys discuss visiting the Oregon wine country and Carson Kitchen in Vegas.&nbsp; Mike explains the concept of "zebra striping" cocktails while deciding what to eat on their next space flight.
#SpaceTravel #ProjectHailMary #ArtemisII #NASA #LasVegas #OregonWine #LakeOswego #CarsonKitchen #KeelVodka https://keelvodka.com/&nbsp;

The Restaurateurs | Zebra Striping, Easter Dinner, Space Food

Getting Arrested & Court Dates

Stop-Start Engines

Mental Health Labels 

Scientists Create A Plant 

A Colorado man with an active arrest warrant was taken into custody after applying to the Commerce City Police Department and requesting a ride‑along. Police say a background check revealed a lengthy criminal history and outstanding warrant, turning what was meant to be a job inquiry into an unexpected arrest at the station. 

Drivers frustrated by automatic stop‑start engines may soon get relief as the Trump administration moves to roll back federal incentives for the fuel‑saving feature. According to The Wall Street Journal, EPA Administrator Lee Zeldin has targeted stop‑start technology — widely disliked by drivers despite its emissions benefits — framing the change as a shift toward consumer choice and away from Obama‑era climate regulations. 

Rising autism and ADHD diagnoses have sparked debate over whether society is finally recognizing long‑missed conditions — or overusing mental‑health labels. This story explores what’s driving the surge, how social awareness and clinical standards have changed, and why the question isn’t just how many diagnoses there are, but who they help and how support is delivered. 

Scientists have engineered a plant capable of producing compounds found in ayahuasca, psychedelic mushrooms, and toad‑derived psychedelics all at once — a development that’s turning heads in both science and ethics circles. The research highlights how advances in synthetic biology are blurring the line between plants and complex psychoactive chemistry, raising questions about regulation, medical research, and how far biotechnology should go when recreating substances traditionally produced in very different organisms. 

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Philip Teresi on KMJ

Weekdays 2-6 PM Pacific on News/Talk 580 AM & 105.9 FM KMJ 

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A Colorado man with an active arrest warrant was taken into custody after applying to the Commerce City Police Department and requesting a ride‑along. Police say a background check revealed a lengthy criminal history and outstanding warrant, turning what was meant to be a job inquiry into an unexpected arrest at the station.&nbsp;
Drivers frustrated by automatic stop‑start engines may soon get relief as the Trump administration moves to roll back federal incentives for the fuel‑saving feature. According to The Wall Street Journal, EPA Administrator Lee Zeldin has targeted stop‑start technology &mdash; widely disliked by drivers despite its emissions benefits &mdash; framing the change as a shift toward consumer choice and away from Obama‑era climate regulations.&nbsp;
Rising autism and ADHD diagnoses have sparked debate over whether society is finally recognizing long‑missed conditions &mdash; or overusing mental‑health labels. This story explores what&rsquo;s driving the surge, how social awareness and clinical standards have changed, and why the question isn&rsquo;t just how many diagnoses there are, but who they help and how support is delivered.&nbsp;
Scientists have engineered a plant capable of producing compounds found in ayahuasca, psychedelic mushrooms, and toad‑derived psychedelics all at once &mdash; a development that&rsquo;s turning heads in both science and ethics circles. The research highlights how advances in synthetic biology are blurring the line between plants and complex psychoactive chemistry, raising questions about regulation, medical research, and how far biotechnology should go when recreating substances traditionally produced in very different organisms.&nbsp;
<hr>
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Getting Arrested, Stop-Start Engines, Mental Health Labels & Scientists Create Plants

This Day In History: Unabomber Arrested 

On this day in history, Americans remember the 1996 arrest of the Unabomber, Ted Kaczynski, at his remote cabin in Montana.  The capture ended a nearly 18‑year nationwide manhunt after a handwritten manifesto — recognized by his brother — led federal investigators to one of the most notorious domestic terror cases in U.S. history. 

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On this day in history, Americans remember the 1996 arrest of the Unabomber, Ted Kaczynski, at his remote cabin in Montana.&nbsp; The capture ended a nearly 18‑year nationwide manhunt after a handwritten manifesto &mdash; recognized by his brother &mdash; led federal investigators to one of the most notorious domestic terror cases in U.S. history.&nbsp;
<hr>
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Philip Teresi on KMJ
Weekdays 2-6 PM Pacific on News/Talk 580 AM &amp; 105.9 FM KMJ 
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Plant Compound vs Breast Cancer Cells & Your Right To Be Anonymous Online

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