Congress and Your Right To Be Anonymous 

Scientists have discovered a plant‑derived molecule called DHL‑11, isolated from Munronia henryi, that kills aggressive triple‑negative breast cancer cells by triggering a cascade of DNA damage, oxidative stress, and apoptosis.

The compound works by disrupting the cancer‑critical enzyme IMPDH2 in an unusual way — destabilizing it rather than simply blocking it — and showed strong effectiveness in both lab tests and patient‑derived tumor organoids. 

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Scientists have discovered a plant‑derived molecule called DHL‑11, isolated from Munronia henryi, that kills aggressive triple‑negative breast cancer cells by triggering a cascade of DNA damage, oxidative stress, and apoptosis.
The compound works by disrupting the cancer‑critical enzyme IMPDH2 in an unusual way &mdash; destabilizing it rather than simply blocking it &mdash; and showed strong effectiveness in both lab tests and patient‑derived tumor organoids.&nbsp;
<hr>
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Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ - Always Online at kmjnow.com 

Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ - Always Online at <a href="https://www.kmjnow.com/">kmjnow.com&nbsp;</a>

Philip Teresi

Ray Appleton began his radio career in Fresno in 1969. That career has taken him from Fresno to London and back. He has been a part of the KMJ team since 1987 and continues to share his thoughts and viewpoints with his very large and loyal audience weekdays from 11am-2pm on Central California's News Talk 580 and 105.9 KMJ!

Ray Appleton began his radio career in Fresno in 1969. That career has taken him from Fresno to London and back. He has been a part of the KMJ team since 1987 and continues to share his thoughts and viewpoints with his very large and loyal audience weekdays from 11am-2pm on Central California's News Talk 580 and 105.9 KMJ!

News Talk 580 & 105.9 KMJ Podcasts

Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ. Politically independent, socially awkward, and fashionably late.

Philip Teresi - Live, Local, and Original: Weekdays from 2:00 to 6:00PM on Central California's News/Talk 580 and 105.9 KMJ. Politically independent, socially awkward, and fashionably late.

Plant Compound vs Breast Cancer Cells & Your Right To Be Anonymous Online  

The Bubble People 

Wendy's 'Chief Tasting Officer' Pays $100K 

'PB4WEGO' Plate Survives The DMV Flush Test

Some People See Aliens While on DMT 

Wendy’s U.S. president Pete Suerken jumped into the viral fast‑food “burger wars” by filming himself grilling and devouring a Baconator, taking big confident bites and praising it as “what a good hamburger should be.”

His video playfully jabbed rivals — including a dig at McDonald’s famously broken ice‑cream machines — and followed viral clips of McDonald’s and Burger King executives awkwardly taste‑testing their own burgers. 

Wendy’s has launched a nationwide search for a “Chief Tasting Officer”, offering a $100,000 salary to a fan willing to taste menu items and create content — a marketing stunt arriving right as fast‑food “burger wars” heat up online between major chains.

The playful job posting requires no formal qualifications beyond “a mouth, a pulse, opinions, and creativity,” and applicants must submit a short video before March 30 to be considered.  

A reminder that’s become a road-trip ritual for plenty of families is officially back on the road in New York. A Long Island grandfather will be allowed to keep his custom “PB4WEGO” license plate after the New York State Department of Motor Vehicles initially deemed it objectionable. 

A new psychedelic retreat calling itself a “SETI for the mind” aims to establish two-way communication with the nonhuman entities people encounter while tripping on DMT. 

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Wendy&rsquo;s U.S. president Pete Suerken jumped into the viral fast‑food &ldquo;burger wars&rdquo; by filming himself grilling and devouring a Baconator, taking big confident bites and praising it as &ldquo;what a good hamburger should be.&rdquo;
His video playfully jabbed rivals &mdash; including a dig at McDonald&rsquo;s famously broken ice‑cream machines &mdash; and followed viral clips of McDonald&rsquo;s and Burger King executives awkwardly taste‑testing their own burgers.&nbsp;
Wendy&rsquo;s has launched a nationwide search for a &ldquo;Chief Tasting Officer&rdquo;, offering a $100,000 salary to a fan willing to taste menu items and create content &mdash; a marketing stunt arriving right as fast‑food &ldquo;burger wars&rdquo; heat up online between major chains.
The playful job posting requires no formal qualifications beyond &ldquo;a mouth, a pulse, opinions, and creativity,&rdquo; and applicants must submit a short video before March 30 to be considered. &nbsp;
A reminder that&rsquo;s become a road-trip ritual for plenty of families is officially back on the road in New York. A Long Island grandfather will be allowed to keep his custom &ldquo;PB4WEGO&rdquo; license plate after the New York State Department of Motor Vehicles initially deemed it objectionable.&nbsp;
A new psychedelic retreat calling itself a &ldquo;SETI for the mind&rdquo; aims to establish two-way communication with the nonhuman entities people encounter while tripping on DMT.&nbsp;
<hr>
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The Burger Wars Remixed for 2026, Vanity Plates & New Aliens 

'In The Heights' Musical at Justin Garza High 

Exports To Canada Collapse

The Justice Department is reviewing whether it wrongly withheld Epstein‑related documents, after reports showed missing FBI interview files involving a woman’s uncorroborated allegations against President Trump.

DOJ says any improperly excluded records will be released once identified. 

Justin Garza High School students are performing In the Heights on an authentic Broadway set — the very one used in past professional productions — thanks to support from Central Unified and Wow Productions.

The rare opportunity has energized the cast, who say the realistic backdrop makes them feel “transported to NYC,” and VIP ticket holders can even take a backstage tour during the show’s March run. 

The Justice Department is reviewing whether it wrongly withheld Epstein‑related documents, after reports showed missing FBI interview files involving a woman’s uncorroborated allegations against President Trump.

DOJ says any improperly excluded records will be released once identified. 

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Philip Teresi on KMJ

Weekdays 2-6 PM Pacific on News/Talk 580 AM & 105.9 FM KMJ 

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The Justice Department is reviewing whether it wrongly withheld Epstein‑related documents, after reports showed missing FBI interview files involving a woman&rsquo;s uncorroborated allegations against President Trump.
DOJ says any improperly excluded records will be released once identified.&nbsp;
Justin Garza High School students are performing In the Heights on an authentic Broadway set &mdash; the very one used in past professional productions &mdash; thanks to support from Central Unified and Wow Productions.
The rare opportunity has energized the cast, who say the realistic backdrop makes them feel &ldquo;transported to NYC,&rdquo; and VIP ticket holders can even take a backstage tour during the show&rsquo;s March run.&nbsp;
The Justice Department is reviewing whether it wrongly withheld Epstein‑related documents, after reports showed missing FBI interview files involving a woman&rsquo;s uncorroborated allegations against President Trump.
DOJ says any improperly excluded records will be released once identified.&nbsp;
<hr>
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DOJ Drops Missing Epstein Files & Exports To Canada Collapse

California Assemblymember Joaquin Arambula spent a month in inpatient rehab for alcohol, marijuana, and gaming addiction, according to divorce filings from his wife, who is seeking over $27,000 per month in support.

Arambula says he completed the program and returned to work, even as he runs for Fresno City Council, but the documents detail escalating dependency issues and strains within the marriage.

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California Assemblymember Joaquin Arambula spent a month in inpatient rehab for alcohol, marijuana, and gaming addiction, according to divorce filings from his wife, who is seeking over $27,000 per month in support.
Arambula says he completed the program and returned to work, even as he runs for Fresno City Council, but the documents detail escalating dependency issues and strains within the marriage.
<hr>
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Plant Compound vs Breast Cancer Cells & Your Right To Be Anonymous Online

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