Every year in the United States, more than 795,000 people have a stroke. And about 610,000 of these are first or new strokes. Stroke is the leading cause of long-term disability. What are the main risk factors for stroke? How can we intervene before a stroke happens? We spoke with Dean Sherzai, MD, PhD, and Ayesha Sherzai, MD, neuroscientists, bestselling authors, and hosts of the Your Brain On podcast, about the types of stroke, important signs to look out for, modifications to lower risk, what post-stroke recovery and care looks like, and additionally how menopause can play a role in stroke.