About 1 in 8 men will face a prostate cancer diagnosis. Early-stage prostate cancer often has no symptoms—so how should men approach screening and advocacy? What disparities do Black men experience that would negatively impact their outcomes? And what can we do about it? We spoke with Otis Brawley, MD, professor of oncology at Johns Hopkins, about the types of prostate cancer, key symptoms, when and how often to screen, and why access to equal treatment is essential for equal outcomes for Black men. He also explains metastatic castration-resistant prostate cancer and why advanced imaging like PSMA PET scans matters. Survivor David Diaz Sr., executive director of The Reluctant Brotherhood, also shares his story of diagnosis, treatment, and the power of support groups for men navigating prostate cancer.