Over 100,000 Americans are waiting for life-saving kidney transplants, with 17 dying each day. Why isn’t universal donation enough? Could xenotransplantation – transplanting gene-edited organs from other species into humans – be the answer? We sat down with Sanjay Gupta, MD, CNN’s chief medical correspondent, to unpack his documentary Animal Pharm and explore the promise and perils of this scientific frontier. We dive into his visits to biosecure pig facilities, ethical questions across faiths, and concerns around infection, cost, and organ rejection. Dr. Gupta also looks ahead to the potential use of pig hearts, lungs, and livers. Tune in for a rare blend of hope, controversy, and cutting-edge science.

Credits
Host: Neha Pathak, MD, FACP, DipABLM
Guest: Sanjay Gupta, MD
Producer/Editor: Lauren Summers
Show Notes: Lauren Summers

Over 100,000 Americans are waiting for life-saving <a href="https://www.webmd.com/a-to-z-guides/what-to-expect-kidney-transplant-surgery" data-testid="linkable-text">kidney transplants</a>, with 17 dying each day. Why isn&rsquo;t universal donation enough? Could xenotransplantation &ndash; transplanting gene-edited organs from other species into humans &ndash; be the answer? We sat down with <a href="https://www.cnn.com/profiles/sanjay-gupta-profile#about" data-testid="linkable-text">Sanjay Gupta, MD</a>, CNN&rsquo;s chief medical correspondent, to unpack his documentary Animal Pharm and explore the promise and perils of this scientific frontier. We dive into his visits to biosecure pig facilities, ethical questions across faiths, and concerns around infection, cost, and organ rejection. Dr. Gupta also looks ahead to the potential use of pig hearts, lungs, and livers. Tune in for a rare blend of hope, controversy, and cutting-edge science.
Credits
<ul>
<li aria-level="1">Host: Neha Pathak, MD, FACP, DipABLM</li>
<li aria-level="1">Guest: Sanjay Gupta, MD</li>
<li aria-level="1">Producer/Editor: Lauren Summers</li>
<li aria-level="1">Show Notes: Lauren Summers</li>
</ul>

WebMD Chief Physician Editor Neha Pathak, MD, and Chief Medical Officer, John Whyte, MD, MPH, explore fascinating stories to find the unexpected things that help us understand our health.

Health Discovered

Exploring Xenotransplantation with Dr. Sanjay Gupta: Inside the Future of Organ Transplants 

A lot of us have heard about “high cortisol” in the context of stress. But Cushing’s syndrome, which has recently been in the news, is something very different. It’s pathologic cortisol excess that can quietly drive certain health problems. We spoke with Lewis Blevins, MD, a neuroendocrinologist specializing in pituitary, hypothalamic, and adrenal disorders, about what cortisol is meant to do, what Cushing’s syndrome really is, why diagnosis is often delayed, and what practical steps to take if you suspect something more than everyday stress. We also discuss the path to an accurate diagnosis and shared decision-making grounded in patient education.

Credits
Host: Neha Pathak, MD, FACP, DipABLM
Producer/Editor: Lauren Summers
Show Notes: Lauren Summers
Guest: Lewis Blevins, MD

A lot of us have heard about &ldquo;high <a href="https://www.webmd.com/a-to-z-guides/what-is-cortisol?ref=ro" data-testid="linkable-text">cortisol</a>&rdquo; in the context of stress. But <a href="https://www.webmd.com/a-to-z-guides/cushing-syndrome" data-testid="linkable-text">Cushing&rsquo;s syndrome</a>, which has recently been in the news, is something very different. It&rsquo;s pathologic cortisol excess that can quietly drive certain health problems. We spoke with <a href="https://pituitaryworldnews.org/about-us/lewis-blevins-md/" data-testid="linkable-text">Lewis Blevins, MD</a>, a neuroendocrinologist specializing in pituitary, hypothalamic, and adrenal disorders, about what cortisol is meant to do, what Cushing&rsquo;s syndrome really is, why diagnosis is often delayed, and what practical steps to take if you suspect something more than everyday stress. We also discuss the path to an accurate diagnosis and shared decision-making grounded in patient education.
Credits
<ul>
<li aria-level="1">Host: Neha Pathak, MD, FACP, DipABLM</li>
<li aria-level="1">Producer/Editor: Lauren Summers</li>
<li aria-level="1">Show Notes: Lauren Summers</li>
<li aria-level="1">Guest: Lewis Blevins, MD</li>
</ul>

High Cortisol or Something More? Understanding Cushing’s Syndrome

For many of us in the “sandwich generation” – those raising kids while caring for aging parents – preventive health can feel like one more impossible task on an already full plate. But prevention isn’t just about protecting your future; it’s about preserving your energy so you can show up for the people who need you right now. We spoke with Eduardo Sanchez, MD, MPH, FAHA, chief medical officer for prevention at the American Heart Association, about a practical framework for health and how sleep, stress, mental well-being, and social connection all play a role in heart health, stroke prevention, and even cognitive health. Taking care of yourself isn’t selfish –  it’s preventive medicine that shapes your future.

Additional resources:
Life’s Essential 8
MyLifeCheck
Your Health Care Journey

Credits
Host: Neha Pathak, MD, FACP, DipABLM
Producer/Editor: Lauren Summers
Show Notes: Lauren Summers
Guest: Eduardo Sanchez, MD, MPH, FAHA

For many of us in the &ldquo;sandwich generation&rdquo; &ndash; those raising kids while caring for aging parents &ndash; <a href="https://www.webmd.com/diet/features/4-steps-healthy-lifestyle" data-testid="linkable-text">preventive health</a> can feel like one more impossible task on an already full plate. But prevention isn&rsquo;t just about protecting your future; it&rsquo;s about preserving your energy so you can show up for the people who need you right now. We spoke with <a href="https://www.heart.org/en/about-us/eduardo-sanchez" data-testid="linkable-text">Eduardo Sanchez, MD, MPH, FAHA</a>, chief medical officer for prevention at the <a href="https://www.heart.org/en/" data-testid="linkable-text">American Heart Association</a>, about a practical framework for health and how sleep, stress, mental well-being, and social connection all play a role in heart health, stroke prevention, and even cognitive health. Taking care of yourself isn&rsquo;t selfish &ndash;&nbsp; it&rsquo;s preventive medicine that shapes your future.
Additional resources: <a href="https://protect.checkpoint.com/v2/r01/___https://www.heart.org/en/healthy-living/healthy-lifestyle/lifes-essential-8___.YzJ1OndlYm1kOmM6ZzozM2M2YzBhMWVhMzQ2ODAxYzU0OTZlNzkwMDc4NjRiZTo3OjNjMTA6ZTllODYyNjVjNDY0MGQ1NjA5ZjdmZDdhNTcwMjQwODE1NjNkMDQwYzFhODQ2N2NjNjZlNTM1MzVkODJhZTdjODpoOlQ6Rg" data-testid="linkable-text">Life&rsquo;s Essential 8 </a><a href="http://mylifecheck/" data-testid="linkable-text">MyLifeCheck </a><a href="https://www.heart.org/en/health-topics/consumer-healthcare" data-testid="linkable-text">Your Health Care Journey</a>
Credits
<ul>
<li aria-level="1">Host: Neha Pathak, MD, FACP, DipABLM</li>
<li aria-level="1">Producer/Editor: Lauren Summers</li>
<li aria-level="1">Show Notes: Lauren Summers</li>
<li>Guest: Eduardo Sanchez, MD, MPH, FAHA</li>
</ul>

Preventive Health for the Sandwich Generation: Putting Your Mask on First

Joint pain is often brushed off as a normal part of aging – but pain that interferes with your daily life doesn’t have to be something you simply live with. In this episode, we talk with Una Makris, MD, MSc, a clinical rheumatologist, about the common joint conditions affecting older adults and what actually helps. From movement and weight management to nutrition and physical therapy, she shares practical, evidence-based strategies to reduce pain and protect your joints. Learn how small, sustainable lifestyle changes can support mobility, independence, and quality of life at every age.

Credits
Host: Neha Pathak, MD, FACP, DipABLM
Producer/Editor: Lauren Summers
Show Notes: Lauren Summers
Guest: Una Makris, MD, MSc

<a href="https://www.webmd.com/pain-management/joint-pain" data-testid="linkable-text">Joint pain</a> is often brushed off as a normal part of aging &ndash; but pain that interferes with your daily life doesn&rsquo;t have to be something you simply live with. In this episode, we talk with <a href="https://breakthroughs.utsouthwestern.edu/women/stories/makris-una.html" data-testid="linkable-text">Una Makris, MD, MSc</a>, a clinical rheumatologist, about the common joint conditions affecting older adults and what actually helps. From movement and weight management to nutrition and physical therapy, she shares practical, evidence-based strategies to reduce pain and protect your joints. Learn how small, sustainable <a href="https://www.webmd.com/arthritis/caring-your-joints" data-testid="linkable-text">lifestyle changes</a> can support mobility, independence, and quality of life at every age.
Credits
<ul>
<li aria-level="1">Host: Neha Pathak, MD, FACP, DipABLM</li>
<li aria-level="1">Producer/Editor: Lauren Summers</li>
<li aria-level="1">Show Notes: Lauren Summers</li>
<li>Guest: Una Makris, MD, MSc</li>
</ul>

Exploring Xenotransplantation with Dr. Sanjay Gupta: Inside the Future of Organ Transplants

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