The baby was still in diapers when the first blister appeared, ballooning red and angry from his pale, newborn skin. Soon, they became a regular feature on the map of his body, along with deep creases in his face when he howled out in pain. A doctor told the parents his LAMB3 gene had a glitch—his body wasn’t making enough of a protein to anchor the outer layer of his skin to the inner ones. For seven years they kept the blisters at bay.