 Mike Blue is the CEO of HistoSonics. The company recently developed a device that uses ultrasound to destroy tumors.

On today’s show, Mike talks about how a garage-built prototype became an FDA-approved machine; changing the company’s story after a failed clinical trial; and why he loves being a salesman but hates most sales pitches.

Mike Blue is the CEO of HistoSonics. The company recently developed a device that uses ultrasound to destroy tumors. On today&rsquo;s show, Mike talks about how a garage-built prototype became an FDA-approved machine; changing the company&rsquo;s story after a failed clinical trial; and why he loves being a salesman but hates most sales pitches.

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with entrepreneurs and engineers tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with&nbsp;entrepreneurs and engineers&nbsp;tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.
iHeartMedia is the exclusive podcast partner of Pushkin Industries.

What's Your Problem?

Every week on What’s Your Problem, entrepreneurs and engineers talk about the future they’re trying to build – and the problems they have to solve to get there.

How do you take a drone delivery service you’ve built in Rwanda and make it work in North Carolina? How do you convince people to buy a house on the Internet? How do you sell thousands of dog ramps to weiner dogs all across America when a pandemic breaks the global supply chain? 

Hosted by former Planet Money host Jacob Goldstein, What’s Your Problem helps listeners understand the problems really smart people are trying to solve right now.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Using Sound Waves to Destroy Tumors

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/ad565e33-42ce-49c5-a766-b39300f9f98c/transcript

Jason Ballard is the co-founder and CEO of ICON. Jason's problem is this: Can you use 3-D printing to build houses that are cheaper, better and more interesting than the houses we build now?

In this episode, Jason explains: 
Why construction methods are so slow to change 
How 3D printing opens up new designs for houses
How building on the Moon shaped the way Icon builds on Earth
The challenge of scaling to printing thousands of houses 

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show ad free, sign up for Pushkin+ 

Jason Ballard is the co-founder and CEO of ICON. Jason's problem is this: Can you use 3-D printing to build houses that are cheaper, better and more interesting than the houses we build now?
In this episode, Jason explains:&nbsp;
<ul>
<li>Why construction methods are so slow to change&nbsp;</li>
<li>How 3D printing opens up new designs for houses</li>
<li>How building on the Moon shaped the way Icon builds on Earth</li>
<li>The challenge of scaling to printing thousands of houses&nbsp;</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/" data-airgap-id="13">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en" data-airgap-id="14">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/" data-airgap-id="15">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm" data-airgap-id="16">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/" data-airgap-id="17">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all" data-airgap-id="18"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en" data-airgap-id="19">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167" data-airgap-id="20">Business History&nbsp;</a></li>
<li>To listen to the show ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin" data-airgap-id="21">Pushkin+</a>&nbsp;</li>
</ul>

Can a Robot Build Better, Cheaper Houses?

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/e789462b-509f-4278-9345-b4e30161f9cd/transcript

Celebrated novelists, countless students and at least one billionaire have recently been accused of using AI in their writing. The most commonly cited AI detector in these cases is called Pangram. 

Max Spero is the co-founder and CEO of Pangram. His problem is this: Can you build tools that reliably detect AI-generated text and images? And a few years from now, will anybody care?

In this episode, Max explains: 
Why AI prose so often sounds the same
How often Pangram makes mistakes
How detectors like Pangram compete with humanizer tools 
Why the big AI companies may not be interested in detection
The shifting norms around AI-generated writing

Celebrated novelists, countless students and at least one billionaire have recently been accused of using AI in their writing. The most commonly cited AI detector in these cases is called Pangram.&nbsp;
Max Spero is the co-founder and CEO of Pangram. His problem is this: Can you build tools that reliably detect AI-generated text and images? And a few years from now, will anybody care?
In this episode, Max explains:&nbsp;
<ul>
<li>Why AI prose so often sounds the same</li>
<li>How often Pangram makes mistakes</li>
<li>How detectors like Pangram compete with humanizer tools&nbsp;</li>
<li>Why the big AI companies may not be interested in detection</li>
<li>The shifting norms around AI-generated writing</li>
</ul>

Did AI Write This?

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/f6ccf617-7502-405d-9aef-b4dd00195c25/transcript

I'm here with a preview of Blockers, a new audiobook from Michael Lewis, the author of Liars Poker, Moneyball, The Big Short and more. In Blockers, Lewis tells the story of a handful of people who dedicated their careers to public service—until the Department of Government Efficiency decided they were a problem. These were people who believed they had a calling—people who kept American's sensitive tax data out of the wrong hands, made sure that politicians and civil servants played by the rules, and figured out how to stop wildfires from destroying suburban neighborhoods—and then discovered they were no longer wanted.

Here's an excerpt from the audiobook. You can buy the audiobook exclusively at blockers.fm. 

I'm here with a preview of Blockers, a new audiobook from Michael Lewis, the author of Liars Poker, Moneyball, The Big Short and more. In Blockers, Lewis tells the story of a handful of people who dedicated their careers to public service&mdash;until the Department of Government Efficiency decided they were a problem. These were people who believed they had a calling&mdash;people who kept American's sensitive tax data out of the wrong hands, made sure that politicians and civil servants played by the rules, and&nbsp;figured out how to stop wildfires from destroying suburban neighborhoods&mdash;and then discovered they were no longer wanted.
Here's an excerpt from the audiobook. You can buy the audiobook exclusively at <a href="http://blockers.fm/" data-airgap-id="17">blockers.fm</a>.&nbsp;

Blockers | A Preview of Michael Lewis's New Audiobook

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/aae25215-6e31-4660-aa49-b4da00f45fa3/transcript

Using Sound Waves to Destroy Tumors

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