Kevin Murach is a professor who studies muscle cells at the University of Missouri. Kevin's problem is this: Can we understand what's going on in our cells when we lift weights – and can we use that knowledge to help people stay healthier as they age?

In this episode, Kevin explains: 
The technology lets scientists watch individual muscle nuclei during exercise
The significance of a cancer gene called Myc that is activated after lifting weights 
How Myc may be linked to cellular age reversal
Why muscle responds less to exercise with age

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show ad free, sign up for Pushkin+ 

Kevin Murach is a professor who studies muscle cells at the University of Missouri. Kevin's problem is this: Can we understand what's going on in our cells when we lift weights &ndash; and can we use that knowledge to help people stay healthier as they age?
In this episode, Kevin explains:&nbsp;
<ul>
<li>The technology lets scientists watch individual muscle nuclei during exercise</li>
<li>The significance of a cancer gene called Myc that is activated after lifting weights&nbsp;</li>
<li>How Myc may be linked to cellular age reversal</li>
<li>Why muscle responds less to exercise with age</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/" data-airgap-id="11">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en" data-airgap-id="12">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/" data-airgap-id="13">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm" data-airgap-id="14">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/" data-airgap-id="15">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all" data-airgap-id="16"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en" data-airgap-id="17">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167" data-airgap-id="18">Business History&nbsp;</a></li>
<li>To listen to the show ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin" data-airgap-id="19">Pushkin+</a>&nbsp;</li>
</ul>

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with entrepreneurs and engineers tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with&nbsp;entrepreneurs and engineers&nbsp;tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.
iHeartMedia is the exclusive podcast partner of Pushkin Industries.

What's Your Problem?

Every week on What’s Your Problem, entrepreneurs and engineers talk about the future they’re trying to build – and the problems they have to solve to get there.

How do you take a drone delivery service you’ve built in Rwanda and make it work in North Carolina? How do you convince people to buy a house on the Internet? How do you sell thousands of dog ramps to weiner dogs all across America when a pandemic breaks the global supply chain? 

Hosted by former Planet Money host Jacob Goldstein, What’s Your Problem helps listeners understand the problems really smart people are trying to solve right now.

iHeartMedia is the exclusive podcast partner of Pushkin Industries.

Can a Cancer Gene Keep Muscles Young?

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/2ea75a15-e8c6-4a0d-b20b-b4f8016a9f25/transcript

Sid Jha is the CEO of an insurance company called Arbol. Sid's problem is this: Can you make insurance cheaper and more accessible by using new technology, new sources of capital, and new ways of thinking about risk?

In this episode, Sid explains: 
How climate change is affecting the risks Arbol covers 
How Arbol is competing with giant insurance companies 
Why prediction market contracts are good for betting, but not hedging

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show ad free, sign up for Pushkin+

Sid Jha is the CEO of an insurance company called Arbol. Sid's problem is this: Can you make insurance cheaper and more accessible by using new technology, new sources of capital, and new ways of thinking about risk?
In this episode, Sid explains:&nbsp;
<ul>
<li>How climate change is affecting the risks Arbol covers&nbsp;</li>
<li>How Arbol is competing with giant insurance companies&nbsp;</li>
<li>Why prediction market contracts are good for betting, but not hedging</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/" data-airgap-id="15">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en" data-airgap-id="16">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/" data-airgap-id="17">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm" data-airgap-id="18">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/" data-airgap-id="19">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all" data-airgap-id="20"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en" data-airgap-id="21">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167" data-airgap-id="22">Business History&nbsp;</a></li>
<li>To listen to the show ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin" data-airgap-id="23">Pushkin+</a></li>
</ul>

Can You Fix Insurance?

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/f4e9b1f6-d7c5-4b6e-bde1-b4ff01444fe8/transcript

Circadian rhythm isn’t just controlled by your brain. Every cell in your body runs on a 24-hour cycle, including your muscle cells. 

Karyn Esser is the chair of the department of physiology and aging at the University of Florida, and she’s a leading expert on circadian rhythm in muscle cells. Karyn's problem is this: How does the circadian rhythm in muscle cells change as we age, and how does exercise help keep our system in sync?

In this episode, Karyn explains: 
How every cell in your body has a clock in it
How muscle clocks prepare cells for work and schedule recovery during rest
How age affects these clocks’ ability to regulate effectively 
Why exercise can improve clock function 
Why jet lag and late-night eating can put your body clocks out of sync 

Connect with us:
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Email us at problem@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn or X 
Listen to Jacob’s other show, Business History 
To listen to the show ad free, sign up for Pushkin+ 

Circadian rhythm isn&rsquo;t just controlled by your brain. Every cell in your body runs on a 24-hour cycle, including your muscle cells.&nbsp;
Karyn Esser is the chair of the department of physiology and aging at the University of Florida, and she&rsquo;s a leading expert on circadian rhythm in muscle cells. Karyn's problem is this: How does the circadian rhythm in muscle cells change as we age, and how does exercise help keep our system in sync?
In this episode, Karyn explains:&nbsp;
<ul>
<li>How every cell in your body has a clock in it</li>
<li>How muscle clocks prepare cells for work and schedule recovery during rest</li>
<li>How age affects these clocks&rsquo; ability to regulate effectively&nbsp;</li>
<li>Why exercise can improve clock function&nbsp;</li>
<li>Why jet lag and late-night eating can put your body clocks out of sync&nbsp;</li>
</ul>
Connect with us:
<ul>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/" data-airgap-id="11">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en" data-airgap-id="12">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/" data-airgap-id="13">Instagram&nbsp;</a></li>
<li>Email us at <a href="mailto:problem@pushkin.fm" data-airgap-id="14">problem@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/" data-airgap-id="15">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all" data-airgap-id="16"> LinkedIn</a> or <a href="https://x.com/pushkinpods?lang=en" data-airgap-id="17">X</a>&nbsp;</li>
<li>Listen to Jacob&rsquo;s other show, <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167" data-airgap-id="18">Business History&nbsp;</a></li>
<li>To listen to the show ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin" data-airgap-id="19">Pushkin+</a>&nbsp;</li>
</ul>

Every Cell in Your Body Has a Clock

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/bd02d39f-d8ab-480a-9d98-b4f101743ea7/transcript

Throughout the next few weeks, every Monday we'll be sharing some of our favorite episodes from Jacob's other show Business History. We hope you enjoy them and if you want to hear more, subscriber to Business History on Apple, Spotify or wherever you get your podcasts.

William Shockley was an electronics genius - he even won a Nobel Prize - but he was an awful boss. Shockley was a cruel, paranoid micromanager. And this annoyed the staff of brilliant young engineers he'd assembled in a quiet town in Northern California. In fact, they quit and set up a company of their own inventing silicon chips. 

Robert Noyce, Gordon Moore and the rest of "The Traitorous Eight" transformed computing, but also blazed a trail for the tech founders who would flock to Silicon Valley and change the world. Members of "The Traitorous Eight" set up Intel and AMD, while also funding businesses such as Google and Slack. 

Connect with us:
Follow Business History on Instagram and TikTok
Follow Jacob Goldstein on LinkedIn, X and Instagram 
Follow Robert Smith on Instagram and X
Email us at businesshistory@pushkin.fm 
Follow Pushkin on Instagram, LinkedIn and X 
To listen to the show ad free, sign up for Pushkin+ 

Throughout the next few weeks, every Monday we'll be sharing some of our favorite episodes from Jacob's other show Business History. We hope you enjoy them and if you want to hear more, subscriber to Business History on <a href="https://podcasts.apple.com/us/podcast/business-history/id1844409167" data-airgap-id="155">Apple</a>, <a href="https://open.spotify.com/show/0eCqHmuyMoj8NXXFHP6wIi?si=b2a62a23c83a4068" data-airgap-id="156">Spotify</a> or wherever you get your podcasts.
William Shockley was an electronics genius - he even won a Nobel Prize - but he was an awful boss. Shockley was a cruel, paranoid micromanager. And this annoyed the staff of brilliant young engineers he'd assembled in a quiet town in Northern California. In fact, they quit and set up a company of their own inventing silicon chips.&nbsp;
Robert Noyce, Gordon Moore and the rest of "The Traitorous Eight" transformed computing, but also blazed a trail for the tech founders who would flock to Silicon Valley and change the world. Members of "The Traitorous Eight" set up Intel and AMD, while also funding businesses such as Google and Slack.&nbsp;
Connect with us:
<ul>
<li>Follow Business History on <a href="https://www.instagram.com/businesshistorypod/" data-airgap-id="12">Instagram</a> and <a href="https://www.tiktok.com/@businesshistorypod" data-airgap-id="13">TikTok</a></li>
<li>Follow Jacob Goldstein on <a href="https://www.linkedin.com/in/jacob-goldstein-888a2441/" data-airgap-id="14">LinkedIn</a>, <a href="https://x.com/jacobgoldstein?lang=en" data-airgap-id="15">X</a> and <a href="https://www.instagram.com/jacobjgoldstein/" data-airgap-id="16">Instagram&nbsp;</a></li>
<li>Follow Robert Smith on <a href="https://www.instagram.com/radiosmith/" data-airgap-id="17">Instagram</a> and <a href="https://x.com/radiosmith" data-airgap-id="18">X</a></li>
<li>Email us at <a href="mailto:businesshistory@pushkin.fm" data-airgap-id="19">businesshistory@pushkin.fm</a>&nbsp;</li>
<li>Follow Pushkin on <a href="https://www.instagram.com/pushkinpods/" data-airgap-id="20">Instagram</a>,<a href="https://www.linkedin.com/company/pushkin-industries/posts/?feedView=all" data-airgap-id="21"> LinkedIn</a> and <a href="https://x.com/pushkinpods?lang=en" data-airgap-id="22">X</a>&nbsp;</li>
<li>To listen to the show ad free, sign up for <a href="https://www.pushkin.fm/join-pushkin" data-airgap-id="23">Pushkin+</a>&nbsp;</li>
</ul>

How a Bad Boss Kickstarted Silicon Valley... from Business History

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/3a0604ba-ef90-4111-a84c-b4ec015368fe/transcript

Can a Cancer Gene Keep Muscles Young?

What's Your Problem?

In 1 playlist(s)

What's Your Problem?

Social links

Follow podcast

Recent clips