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Bettina Ryll, Kjetil Taskén & Anni Lepland: PRIME-ROSE & EU Joint Action

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In this episode of the Vital Health Podcast, host Duane Schulthess speaks with three leaders advancing precision cancer medicine implementation in Europe:

They explore how Europe’s new Joint Action can accelerate equitable precision oncology, what PRIME-ROSE has learned from aggregating data across national pragmatic trials, and why a distributed, bottom-up model with strong patient involvement and industry collaboration is key to scaling access and evidence generation across member states.

Key Topics:

  • EU Joint Action: Governmental collaboration, precision prevention, diagnosis, and treatment, precision follow-up.

  • PRIME-ROSE Collaboration: Data sharing agreements, aggregated cohorts, common biomarker definitions, and monthly alignment.

  • Patient Need First: Options after standard care, access to molecular profiling, pragmatic protocols, and learning from each case.

  • Widening Country Gaps: Workforce shortages, national coordination, digital tools, and equitable access to innovative drugs.

  • Industry and Access: Single point of entry for drugs, managed entry agreements, off-label registries, and scaling trials across Europe.

Opinions expressed are those of the speakers.

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Duane Schulthess, Managing Director of Vital Tran…
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