Richard Sherman and Mitch Eisenstein break down and predict every major matchup in NFL Week 4, including Denver Broncos vs. San Francisco 49ers, Los Angeles Chargers vs. Seattle Seahawks, Kansas City Chiefs vs. Las Vegas Raiders, Detroit Lions vs. Carolina Panthers, and Buffalo Bills vs. New England Patriots. Richard shares his updated NFL power rankings, explains why the Niners remain his No. 1 team, previews a potential Raiders’ upset of Patrick Mahomes and the Chiefs, and names the Panthers over the Lions as his Week 4 upset alert. The guys also discuss the Seahawks’ response to their loss to Washington, the Bears’ rise with Case Keenum, Josh Allen and the Bills facing Drake Maye’s Patriots, and whether the Rams can bounce back against the Eagles. Plus, Sherman reacts to the reported trade talks involving Joey Porter Jr. and the Detroit Lions, J.J. McCarthy landing with the New York Giants, Tyreek Hill’s potential next team, Brian Flores’ revenge game against Miami, and the biggest NFL storylines heading into Week 4.