Colin gives his instant reaction to the Niners losing Jimmy Garoppolo for the year with a foot injury, if they should take a big swing at Tom Brady, what Joe Burrow’s 3-0 record against Patrick Mahomes means in the AFC picture, why the Raiders and Chargers are headed in opposite directions, and if Sean Payton could replace Brandon Staley. Finally, Colin previews the CFB Playoff Final Four and gives his national title game prediction.

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