Hour 3 of The Clay Travis and Buck Sexton Show dives into a wide-ranging set of political, cultural, and health‑policy topics, beginning with updates on Hillary Clinton’s ongoing testimony in the Epstein investigation, Bill Clinton’s scheduled appearance the following day, and new economic news showing mortgage rates dropping below 6% for the first time in four years. Clay and Buck preview a major conversation planned for tomorrow’s show about escalating tensions with Iran, noting that Middle East negotiations have collapsed and raising the question of whether the United States could be drawn into direct conflict. They also discuss a mysterious developing story out of Cuba, where Americans were reportedly killed by Cuban military forces near the island—an event they describe as highly unusual, geopolitically strange, and potentially signaling a much deeper crisis.

The hour then pivots to one of the week's most talked‑about cultural flashpoints: the U.S. men’s hockey team facing backlash from the sports media and Democratic commentators for visiting President Trump at the White House. New Jersey hockey fans deliver a resounding counter‑message, showering the players with cheers and “USA” chants, while loudly booing the state’s new Democratic governor. Clay and Buck use this moment to illustrate how the sports‑media industry became dominated by left‑wing politics after the Colin Kaepernick era, how traditional sports journalism lost value when real‑time information became instant, and why so many sportswriters now rely on ideological content to justify their roles. They argue that most fans simply want sports, not politics, and that AI is poised to replace much of the current sports‑media class.

From there, they return to the Cuba incident. Buck outlines competing theories—ranging from a tragic error, to an overreaction by Cuban authorities, to a potential intelligence‑related provocation reminiscent of historical “Gulf of Tonkin”‑style events. Clay takes a more forceful stance, arguing that after 70 years of dysfunction, the United States should eliminate Cuba’s communist regime entirely and rebuild a free, prosperous, capitalist Cuba aligned with American interests. Buck notes that large segments of the South Florida Cuban‑American community would strongly support such an outcome.

At the bottom of the hour, FDA Commissioner Dr. Marty Makary joins the program for a detailed and rapid‑fire interview. He announces that the FDA just approved a new drug in 44 days—an unprecedented turnaround—and outlines structural reforms intended to speed drug approvals without sacrificing safety. Dr. Makary explains new pathways designed to fast‑track treatments for rare diseases, which collectively affect one in eleven Americans. He discusses the surge in popularity of GLP‑1 weight‑loss drugs, the unregulated gray zone around peptides, and how the FDA is distinguishing legitimate therapies from unauthorized copycats. He also details sweeping reforms to U.S. nutrition guidance, including rewriting the federal food pyramid, emphasizing protein‑rich whole foods, and eliminating taxpayer funding for sugary drinks and ultra‑processed foods in federal nutrition programs.

The conversation then turns to the modern explosion in childhood allergies. Dr. Makary explains that a major cause may have been decades of incorrect medical advice telling parents to avoid feeding young children allergenic foods until age three. He clarifies that early introduction of foods like peanut butter between five and seven months can reduce allergy risk by more than 80%. He also outlines the FDA’s improved communication efforts, updates to vaccine guidance, and ongoing scientific reevaluation of the COVID‑era booster policies that once lacked strong data.

As the hour wraps up, the hosts press Dr. Makary on the post‑COVID landscape. He notes that this year’s flu has been more prevalent than COVID, that the flu shot was a poor match for circulating strains, and that the public health response to COVID—especially school closures, masking toddlers, and approving annual boosters without adequate clinical data—was a historic failure. He outlines key FDA goals going forward, including pursuing cures for type 1 diabetes, advanced therapies for certain late‑stage cancers, improved treatments for PTSD in veterans, and a universal flu vaccine providing lifelong protection.

Hour 3 closes on a lighter note, with Clay and Buck joking about Clay’s goal of bench pressing 315 pounds, reflecting on how few public voices were willing to challenge mask mandates during the COVID years, and previewing the next day’s topics: whether the U.S. may be headed toward war with Iran, Kamala Harris appearing to signal a 2028 run, and Bill Clinton’s upcoming Epstein testimony.

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