Today's biggest winners and losers in the stock market.

On this episode of Stock Movers:

- Booking Holdings (BKNG) shares fell on Tuesday after the online travel agent said the Middle East conflict impacted its first quarter results to varying degrees. Its 2Q and full-year forecasts miss estimates. Peer Expedia, which reports May 7, is down 5.0%.

- Starbucks (SBUX) stocks jumped after the coffee chain reported better-than-expected quarterly results and said it now sees comparable sales rising at least 5% this year, up from its previous view of 3% or more.

- Centene (CNC) shares rose after first-quarter profit exceeded Wall Street expectations and the company raised its outlook for the year in the latest sign of recovery for a US health insurance sector coming off a terrible year. Adjusted earnings of $3.37 a share surpassed all analyst estimates in a Bloomberg survey. A key gauge of medical costs came in more favorable than Wall Street views. The company boosted its earnings outlook for the year by 40 cents a share, it said in a statement Tuesday.