Board-certified dermatologists Dr. Ted Lain and pediatric dermatology expert Dr. Lisa Swanson break down the latest pediatric dermatology treatments in this episode of the Science of Skin Podcast.

Topics covered: atopic dermatitis (eczema) treatment updates including Zoryve, Vtama, and Opzelura; pediatric psoriasis therapies including Zoryve foam, Tremfya, and the oral IL-23 inhibitor Sotyktu; GLP-1 medications (Ozempic/semaglutide) for psoriasis and hidradenitis suppurativa; spironolactone dosing for teenage female acne; hemangioma treatment with timolol, propranolol (Hemangiol), and nadolol; molluscum contagiosum treatment with Ycanth and berdazimer gel (Zelsuvmi); and JAK inhibitors (Litfulo, Olumiant, Rinvoq) for pediatric alopecia areata and early intervention strategies.

Plus: a lighthearted dive into Bachelor Nation, Secret Lives of Mormon Wives, Love Island, and Taylor Swift's wedding buzz.

Send episode topic ideas to questions@scienceofskinsummit.com. Subscribe and leave a 5-star rating to support the show.

Join us at the Science of Skin Summit, September 17–20 in Austin, Texas, and the Longevity Conference, February 19–21 in Scottsdale, Arizona. Learn more at scienceofskinsummit.com.

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Board-certified dermatologists Dr. Ted Lain and pediatric dermatology expert Dr. Lisa Swanson break down the latest pediatric dermatology treatments in this episode of the Science of Skin Podcast.
Topics covered: atopic dermatitis (eczema) treatment updates including Zoryve, Vtama, and Opzelura; pediatric psoriasis therapies including Zoryve foam, Tremfya, and the oral IL-23 inhibitor Sotyktu; GLP-1 medications (Ozempic/semaglutide) for psoriasis and hidradenitis suppurativa; spironolactone dosing for teenage female acne; hemangioma treatment with timolol, propranolol (Hemangiol), and nadolol; molluscum contagiosum treatment with Ycanth and berdazimer gel (Zelsuvmi); and JAK inhibitors (Litfulo, Olumiant, Rinvoq) for pediatric alopecia areata and early intervention strategies.
Plus: a lighthearted dive into Bachelor Nation, Secret Lives of Mormon Wives, Love Island, and Taylor Swift's wedding buzz.
Send episode topic ideas to <a href="mailto:questions@scienceofskinsummit.com">questions@scienceofskinsummit.com</a>. Subscribe and leave a 5-star rating to support the show.
Join us at the Science of Skin Summit, September 17&ndash;20 in Austin, Texas, and the Longevity Conference, February 19&ndash;21 in Scottsdale, Arizona. Learn more at <a href="https://scienceofskinsummit.com/">scienceofskinsummit.com</a>.
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Pediatric Dermatology Guide: Eczema, Psoriasis, Alopecia, Acne & Hemangiomas

Up to 70% of people say they have sensitive skin — but is it really a diagnosis, or something else entirely? Dr. Patti Farris and Dr. Ted Lain break down the biology dermatologists are still trying to figure out.

In this episode of the Science of Skin Podcast, Patti and Ted dig into a 15,000+ person global study on sensitive skin prevalence, and explore the science behind why skin reacts with no visible cause — covering TRPV1 and TRPA1 receptor activity, neuropeptide release (substance P, CGRP), and the connection to rosacea. They also unpack the exposome: how pollution, UV exposure, hormones, menopause, and the skin microbiome all play a role, including a deep dive into aryl hydrocarbon receptor (AHR) activation and inflammation. The episode closes with a new comparative cleanser study using D-Squame tape stripping and colorimetric index of mildness (SIM) testing, showing how Cetaphil Gentle Skin Cleanser performs against other "gentle" cleansers on the market.

🔔 Subscribe for new episodes of the Science of Skin Podcast, bringing you cutting-edge dermatology and skincare science.

RESOURCES & LINKS
📧 Questions or episode ideas? Email: inquiry@scienceofskinsummit.com
🎟️ Join us in Austin, TX — Science of Skin Summit, Sept 17–20, 2026
🎟️ Science of Skin Longevity Summit — Scottsdale, AZ, Feb 2027
🌐 Learn more: scienceofskinsummit.com

Case Study Link: A Comparative Analysis of 8 Facial Cleansers Using Corneosurfametry Reveals Differentiated Irritation Potential - JDDonline - Journal of Drugs in Dermatology

This episode is sponsored by Galderma.

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Up to 70% of people say they have sensitive skin &mdash; but is it really a diagnosis, or something else entirely? Dr. Patti Farris and Dr. Ted Lain break down the biology dermatologists are still trying to figure out.
In this episode of the Science of Skin Podcast, Patti and Ted dig into a 15,000+ person global study on sensitive skin prevalence, and explore the science behind why skin reacts with no visible cause &mdash; covering TRPV1 and TRPA1 receptor activity, neuropeptide release (substance P, CGRP), and the connection to rosacea. They also unpack the exposome: how pollution, UV exposure, hormones, menopause, and the skin microbiome all play a role, including a deep dive into aryl hydrocarbon receptor (AHR) activation and inflammation. The episode closes with a new comparative cleanser study using D-Squame tape stripping and colorimetric index of mildness (SIM) testing, showing how Cetaphil Gentle Skin Cleanser performs against other "gentle" cleansers on the market.
🔔 Subscribe for new episodes of the Science of Skin Podcast, bringing you cutting-edge dermatology and skincare science.
RESOURCES &amp; LINKS 📧 Questions or episode ideas? Email: <a href="mailto:inquiry@scienceofskinsummit.com">inquiry@scienceofskinsummit.com</a> 🎟️ Join us in Austin, TX &mdash; Science of Skin Summit, Sept 17&ndash;20, 2026 🎟️ Science of Skin Longevity Summit &mdash; Scottsdale, AZ, Feb 2027 🌐 Learn more: scienceofskinsummit.com
Case Study Link:&nbsp;<a href="https://jddonline.com/articles/comparative-analysis-of-8-facial-cleansers-using-corneosurfametry-reveals-differentiated-irritation-potential-S1545961626P10028X" data-saferedirecturl="https://www.google.com/url?q=https://jddonline.com/articles/comparative-analysis-of-8-facial-cleansers-using-corneosurfametry-reveals-differentiated-irritation-potential-S1545961626P10028X&amp;source=gmail&amp;ust=1784041120135000&amp;usg=AOvVaw3q5GtGKdnjgRDvpMqIwiTD">A Comparative Analysis of 8 Facial Cleansers Using Corneosurfametry Reveals Differentiated Irritation Potential - JDDonline - Journal of Drugs in Dermatology</a>
This episode is sponsored by Galderma.
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Sensitive Skin Syndrome: What's Really Happening to Your Skin

🎧 In this episode of the Science of Skin Podcast, host Dr. Patty Farris sits down with Dr. Rishi Chopra — a Harvard-trained, fellowship-trained cosmetic dermatologist from the Mass General Wellman Center for Photomedicine — for a deep dive into the evolution of fractionated laser resurfacing.

Dr. Chopra breaks down how fractional photothermolysis, first described by Drs. Rox Anderson and Dieter Manstein in 2004, transformed dermatology by moving away from painful, high-downtime ablative resurfacing toward safer, more effective treatments. He walks through the progression from the original Fraxel Restore to the Fraxel Dual and the newly launched Fraxel FTX, explaining the science behind each wavelength (1550nm, 1927nm) and how these advances made treatments more tolerable, more precise, and safer for patients with skin of color.

The conversation also covers a remarkable patient case: a young man with severe acne scarring who saw nearly 100% improvement after six Fraxel FTX treatments — illustrating just how far this technology has come. Dr. Chopra then discusses the Clear + Brilliant Touch, a lower-downtime "lunchtime facial" option that's especially popular with younger patients and serves as both an entry point and a maintenance tool for building long-term patient trust.

Whether you're a dermatology professional refining your device menu or simply curious about the science behind modern laser resurfacing, this episode offers a comprehensive, practical look at how far fractionated laser technology has come — and where it's headed next.

In this episode:
The history of ablative vs. fractionated laser resurfacing
Fraxel Restore → Dual → FTX: what changed and why
Treating acne scars and photoaging safely in skin of color
A dramatic real-world patient case study
Clear + Brilliant Touch as a "lunchtime facial" option
Building patient trust through a tiered treatment approach

This episode is sponsored by Solta Medical. Dr. Chopra has been compensated by Solta Medical for his participation.

Full prescribing and safety information for Fraxel and Clear + Brilliant laser systems is available at www.fraxel.com/HCP and www.clearandbrilliant.com/HCP.

🎧 In this episode of the Science of Skin Podcast, host Dr. Patty Farris sits down with Dr. Rishi Chopra &mdash; a Harvard-trained, fellowship-trained cosmetic dermatologist from the Mass General Wellman Center for Photomedicine &mdash; for a deep dive into the evolution of fractionated laser resurfacing.
Dr. Chopra breaks down how fractional photothermolysis, first described by Drs. Rox Anderson and Dieter Manstein in 2004, transformed dermatology by moving away from painful, high-downtime ablative resurfacing toward safer, more effective treatments. He walks through the progression from the original Fraxel Restore to the Fraxel Dual and the newly launched Fraxel FTX, explaining the science behind each wavelength (1550nm, 1927nm) and how these advances made treatments more tolerable, more precise, and safer for patients with skin of color.
The conversation also covers a remarkable patient case: a young man with severe acne scarring who saw nearly 100% improvement after six Fraxel FTX treatments &mdash; illustrating just how far this technology has come. Dr. Chopra then discusses the Clear + Brilliant Touch, a lower-downtime "lunchtime facial" option that's especially popular with younger patients and serves as both an entry point and a maintenance tool for building long-term patient trust.
Whether you're a dermatology professional refining your device menu or simply curious about the science behind modern laser resurfacing, this episode offers a comprehensive, practical look at how far fractionated laser technology has come &mdash; and where it's headed next.
In this episode:
<ul>
<li>The history of ablative vs. fractionated laser resurfacing</li>
<li>Fraxel Restore &rarr; Dual &rarr; FTX: what changed and why</li>
<li>Treating acne scars and photoaging safely in skin of color</li>
<li>A dramatic real-world patient case study</li>
<li>Clear + Brilliant Touch as a "lunchtime facial" option</li>
<li>Building patient trust through a tiered treatment approach</li>
</ul>
This episode is sponsored by Solta Medical. Dr. Chopra has been compensated by Solta Medical for his participation.
Full prescribing and safety information for Fraxel and Clear + Brilliant laser systems is available at <a href="http://www.fraxel.com/HCP">www.fraxel.com/HCP</a> and <a href="http://www.clearandbrilliant.com/HCP">www.clearandbrilliant.com/HCP</a>.

The Evolution of Fractionated Lasers: Fraxel, FTX & Clear + Brilliant with Dr. Rishi Chopra

Dr. Ted Lain sits down with board-certified pediatric dermatologist Dr. Nnenna Agim to discuss the toddler indication for roflumilast cream (Zoryve) and how non-steroidal topicals are changing the treatment landscape for atopic dermatitis, psoriasis, and seborrheic dermatitis in children.

In this episode of the Science of Skin Podcast, Dr. Agim shares her real-world clinical experience using roflumilast cream 0.05% (ages 2-5) and 0.15% (ages 6+) as a steroid-sparing alternative for pediatric eczema, explaining why more families are requesting non-steroidal options from the start of treatment. The conversation covers:
Why roflumilast (Zoryve) is safe to use on any body surface, including the face and skin folds
Managing parent expectations and proper dosing to avoid overuse
The importance of pairing roflumilast with ceramide-rich, fragrance-free moisturizers like CeraVe, La Roche-Posay, and Vaseline
How roflumilast compares to crisaborole (Eucrisa) and topical corticosteroids in tolerability
Treating psoriasis and seborrheic dermatitis in children with roflumilast foam and cream
Skin barrier repair, ceramide production, and the role of the acid mantle in atopic dermatitis
Caring for textured hair and scalp conditions in pediatric patients
Real patient outcomes and quality-of-life improvements with Zoryve

This episode is sponsored by Arcutis Biotherapeutics and is part of an ongoing series exploring roflumilast formulation science. Don't miss the related episode on roflumilast's formulation with Dr. Chris Bunick.

Learn more about the Science of Skin Summit (Austin, TX) and the new Science of Skin Longevity Summit (Scottsdale, AZ, Feb 2027) at scienceofskinsummit.com.

🔔 Subscribe and leave a 5-star rating to support the show!

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Dr. Ted Lain sits down with board-certified pediatric dermatologist Dr. Nnenna Agim to discuss the toddler indication for roflumilast cream (Zoryve) and how non-steroidal topicals are changing the treatment landscape for atopic dermatitis, psoriasis, and seborrheic dermatitis in children.
In this episode of the Science of Skin Podcast, Dr. Agim shares her real-world clinical experience using roflumilast cream 0.05% (ages 2-5) and 0.15% (ages 6+) as a steroid-sparing alternative for pediatric eczema, explaining why more families are requesting non-steroidal options from the start of treatment. The conversation covers:
<ul>
<li>Why roflumilast (Zoryve) is safe to use on any body surface, including the face and skin folds</li>
<li>Managing parent expectations and proper dosing to avoid overuse</li>
<li>The importance of pairing roflumilast with ceramide-rich, fragrance-free moisturizers like CeraVe, La Roche-Posay, and Vaseline</li>
<li>How roflumilast compares to crisaborole (Eucrisa) and topical corticosteroids in tolerability</li>
<li>Treating psoriasis and seborrheic dermatitis in children with roflumilast foam and cream</li>
<li>Skin barrier repair, ceramide production, and the role of the acid mantle in atopic dermatitis</li>
<li>Caring for textured hair and scalp conditions in pediatric patients</li>
<li>Real patient outcomes and quality-of-life improvements with Zoryve</li>
</ul>
This episode is sponsored by Arcutis Biotherapeutics and is part of an ongoing series exploring roflumilast formulation science. Don't miss the related episode on roflumilast's formulation with Dr. Chris Bunick.
Learn more about the Science of Skin Summit (Austin, TX) and the new Science of Skin Longevity Summit (Scottsdale, AZ, Feb 2027) at <a href="https://scienceofskinsummit.com/">scienceofskinsummit.com</a>.
🔔 Subscribe and leave a 5-star rating to support the show!
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Roflumilast Cream for Toddler Eczema, Psoriasis & Seborrheic Dermatitis

In this episode of the Science of Skin podcast, board-certified dermatologist Dr. Patti Farris sits down with Golden Follicle Award winner and hair restoration surgery pioneer Dr. Nicole Rogers to break down everything you need to know about hair loss treatment — from trending social media remedies to cutting-edge clinical trials.

Whether you're experiencing male pattern baldness, female pattern hair loss, postpartum shedding, or hair thinning from GLP-1 weight loss drugs, this episode covers it all. Dr. Rogers shares her expert framework for building a personalized hair loss treatment plan and explains exactly when to move from over-the-counter solutions to prescription therapies.

Topics covered include:
Rosemary oil, pumpkin seed oil & nutraceuticals — do they actually work?
Oral minoxidil vs. topical minoxidil — what the latest research shows
Extended-release oral minoxidil (Veridermix) — the next FDA-approved hair loss drug?
Finasteride and dutasteride for men and women — dosing, safety, and the truth about post-finasteride syndrome
Spironolactone for pre-menopausal women with hair loss
Topical finasteride and dutasteride via compounding pharmacy
Low-level laser/red light therapy (LLLT) for hair growth — what the science really says
PRP (platelet-rich plasma) injections — when they help and when they're overhyped
Exosomes for hair loss — promise vs. FDA concerns
PP405 and stem cell activation — the groundbreaking new molecule in clinical trials
FUE vs. FUT hair transplant surgery — what's right for you
No-shave FUE — the emerging frontier in hair restoration
Hair transplants for women — why strip harvesting remains the gold standard

If you're searching for answers on androgenetic alopecia, alopecia areata, telogen effluvium, scalp health, DHT blockers, hair regrowth treatments, or the best dermatologist-recommended solutions for thinning hair, this is the episode you've been waiting for. Dr. Rogers brings decades of clinical expertise, peer-reviewed research, and real patient outcomes to help you navigate the overwhelming world of hair loss — with science, not social media hype.

🎙️ Subscribe, leave a review, and share with anyone on their hair loss journey. New episodes available on Apple Podcasts and Spotify.

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

In this episode of the Science of Skin podcast, board-certified dermatologist Dr. Patti Farris sits down with Golden Follicle Award winner and hair restoration surgery pioneer Dr. Nicole Rogers to break down everything you need to know about hair loss treatment &mdash; from trending social media remedies to cutting-edge clinical trials.
Whether you're experiencing male pattern baldness, female pattern hair loss, postpartum shedding, or hair thinning from GLP-1 weight loss drugs, this episode covers it all. Dr. Rogers shares her expert framework for building a personalized hair loss treatment plan and explains exactly when to move from over-the-counter solutions to prescription therapies.
Topics covered include:
<ul>
<li>Rosemary oil, pumpkin seed oil &amp; nutraceuticals &mdash; do they actually work?</li>
<li>Oral minoxidil vs. topical minoxidil &mdash; what the latest research shows</li>
<li>Extended-release oral minoxidil (Veridermix) &mdash; the next FDA-approved hair loss drug?</li>
<li>Finasteride and dutasteride for men and women &mdash; dosing, safety, and the truth about post-finasteride syndrome</li>
<li>Spironolactone for pre-menopausal women with hair loss</li>
<li>Topical finasteride and dutasteride via compounding pharmacy</li>
<li>Low-level laser/red light therapy (LLLT) for hair growth &mdash; what the science really says</li>
<li>PRP (platelet-rich plasma) injections &mdash; when they help and when they're overhyped</li>
<li>Exosomes for hair loss &mdash; promise vs. FDA concerns</li>
<li>PP405 and stem cell activation &mdash; the groundbreaking new molecule in clinical trials</li>
<li>FUE vs. FUT hair transplant surgery &mdash; what's right for you</li>
<li>No-shave FUE &mdash; the emerging frontier in hair restoration</li>
<li>Hair transplants for women &mdash; why strip harvesting remains the gold standard</li>
</ul>
If you're searching for answers on androgenetic alopecia, alopecia areata, telogen effluvium, scalp health, DHT blockers, hair regrowth treatments, or the best dermatologist-recommended solutions for thinning hair, this is the episode you've been waiting for. Dr. Rogers brings decades of clinical expertise, peer-reviewed research, and real patient outcomes to help you navigate the overwhelming world of hair loss &mdash; with science, not social media hype.
🎙️ Subscribe, leave a review, and share with anyone on their hair loss journey. New episodes available on Apple Podcasts and Spotify.
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Hair Loss Treatments: Dr. Nicole Rogers on What Actually Works

Are you a dermatologist curious about clinical research — or a seasoned trialist looking to reignite your passion? In this episode of the Science of Skin Podcast, Dr. Ted Lane (Austin, TX) sits down with Dr. Jason Hawkes, Chief Scientific Officer at Oregon Medical Research Center, to pull back the curtain on what it really means to build a career in dermatology clinical trials.

From navigating the growing complexity of modern trial protocols to reframing the pharma-physician relationship, Ted and Jason share candid insights that only experienced clinical trialists can offer. They discuss how running trials makes you a sharper diagnostician, why medical dermatology remains one of the most rewarding specialties, and how industry partnerships open unexpected academic and commercial doors.

You'll also hear their honest takes on mentorship — including the must-read JAMA article Mentorship Malpractice — and why thinking of your career as a lattice, not a ladder may be the most liberating shift you can make.

Whether you're five years into practice or just starting out, this episode is packed with hard-won wisdom on building a meaningful, intellectually stimulating career in dermatology.

📩 Questions or future episode ideas? Email: questions@scienceofskinpodcast.com

Topics Covered:
How clinical trials combat physician burnout
The real motivations behind patient participation in trials
How to interpret clinical data like a trialist
Navigating the evolving complexity of trial conduct
Building industry relationships the right way
The importance of mentorship in dermatology research
Career advice: "lattice, not a ladder"

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Are you a dermatologist curious about clinical research &mdash; or a seasoned trialist looking to reignite your passion? In this episode of the Science of Skin Podcast, Dr. Ted Lane (Austin, TX) sits down with Dr. Jason Hawkes, Chief Scientific Officer at Oregon Medical Research Center, to pull back the curtain on what it really means to build a career in dermatology clinical trials.
From navigating the growing complexity of modern trial protocols to reframing the pharma-physician relationship, Ted and Jason share candid insights that only experienced clinical trialists can offer. They discuss how running trials makes you a sharper diagnostician, why medical dermatology remains one of the most rewarding specialties, and how industry partnerships open unexpected academic and commercial doors.
You'll also hear their honest takes on mentorship &mdash; including the must-read JAMA article Mentorship Malpractice &mdash; and why thinking of your career as a lattice, not a ladder may be the most liberating shift you can make.
Whether you're five years into practice or just starting out, this episode is packed with hard-won wisdom on building a meaningful, intellectually stimulating career in dermatology.
📩 Questions or future episode ideas? Email: <a href="mailto:questions@scienceofskinpodcast.com">questions@scienceofskinpodcast.com</a>
Topics Covered:
<ul>
<li>How clinical trials combat physician burnout</li>
<li>The real motivations behind patient participation in trials</li>
<li>How to interpret clinical data like a trialist</li>
<li>Navigating the evolving complexity of trial conduct</li>
<li>Building industry relationships the right way</li>
<li>The importance of mentorship in dermatology research</li>
<li>Career advice: "lattice, not a ladder"</li>
</ul>
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Clinical Trials in Dermatology: Insider Tips from Top Researchers

What really separates roflumilast (Zoryve) from other PDE4 inhibitors — and why does it matter for your patients with atopic dermatitis, psoriasis, or seborrheic dermatitis? In this episode, Dr. Ted Lane sits down with Dr. Chris Bunick, Associate Professor of Dermatology at Yale School of Medicine and Editor-in-Chief of Dermatology Times, for a deep dive into the biochemistry, formulation science, and clinical implications behind this breakthrough topical treatment.

In this episode, you'll learn:
Why roflumilast binds PDE4 with 200x more potency than apremilast — and 1,000x more than crisaborole
How cyclic AMP inhibition controls upstream cytokine pathways (TH1, TH2, TH17) across multiple inflammatory skin diseases
The science behind the Crotofos emulsifier — and why the right emulsifier protects the skin barrier instead of stripping ceramides
Why formulating at pH 5.5 matters for filaggrin, keratin, and barrier integrity
How the roflumilast foam is specifically engineered for scalp conditions and hair-bearing areas
What's next in topical formulation innovation — from targeted dermal delivery to longevity skincare

Whether you're a dermatologist, resident, PA, NP, or skincare enthusiast who wants to understand the why behind cutting-edge topicals, this episode is packed with clinical and scientific insight you won't find anywhere else.

🎙️ This episode is sponsored by Arcutis Biotherapeutics, maker of roflumilast cream and foam.

📧 Send your questions to: questions@scienceofskinnsummit.com

📅 Science of Skin Summit — September 19–21, Austin, TX

📅 Longevity Meeting — February 19 - 21, Scottsdale, AZ

Subscribe, leave a 5-star review, and follow Dr. Bunick's podcast: ABCDs in Dermatology.

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

What really separates roflumilast (Zoryve) from other PDE4 inhibitors &mdash; and why does it matter for your patients with atopic dermatitis, psoriasis, or seborrheic dermatitis? In this episode, Dr. Ted Lane sits down with Dr. Chris Bunick, Associate Professor of Dermatology at Yale School of Medicine and Editor-in-Chief of Dermatology Times, for a deep dive into the biochemistry, formulation science, and clinical implications behind this breakthrough topical treatment.
In this episode, you'll learn:
<ul>
<li>Why roflumilast binds PDE4 with 200x more potency than apremilast &mdash; and 1,000x more than crisaborole</li>
<li>How cyclic AMP inhibition controls upstream cytokine pathways (TH1, TH2, TH17) across multiple inflammatory skin diseases</li>
<li>The science behind the Crotofos emulsifier &mdash; and why the right emulsifier protects the skin barrier instead of stripping ceramides</li>
<li>Why formulating at pH 5.5 matters for filaggrin, keratin, and barrier integrity</li>
<li>How the roflumilast foam is specifically engineered for scalp conditions and hair-bearing areas</li>
<li>What's next in topical formulation innovation &mdash; from targeted dermal delivery to longevity skincare</li>
</ul>
Whether you're a dermatologist, resident, PA, NP, or skincare enthusiast who wants to understand the why behind cutting-edge topicals, this episode is packed with clinical and scientific insight you won't find anywhere else.
🎙️ This episode is sponsored by Arcutis Biotherapeutics, maker of roflumilast cream and foam.
📧 Send your questions to: <a href="mailto:questions@scienceofskinnsummit.com">questions@scienceofskinnsummit.com</a>
📅 Science of Skin Summit &mdash; September 19&ndash;21, Austin, TX
📅 Longevity Meeting &mdash; February 19 - 21, Scottsdale, AZ
Subscribe, leave a 5-star review, and follow Dr. Bunick's podcast: ABCDs in Dermatology.
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Roflumilast vs. Crisaborole: The PDE4 Science That Changes Everything

Big news for nurse practitioners and physician assistants in dermatology! Dr. Patti Farris is joined by PA and dermatology leader Kristin Rygg to announce a brand-new NP/PA track at the 2026 Science of Skin Summit — a first-of-its-kind opportunity for advanced practice providers to learn alongside their physician colleagues.

In this episode, you'll hear:
Why this NP/PA-dedicated track was created and what makes it different
A full breakdown of the September 10th agenda — from immunology and inflammatory skin disease to biologics, GLP-1s, and advanced skincare ingredients
How the curriculum is designed for every career stage, from new grads to seasoned practitioners
What to expect at the full Summit (September 17–20, 2026), including case-based learning, product theaters, and a longevity track
How NPs and PAs will be featured on the main stage for the first time

Whether you're a PA, NP, dermatologist, or practice owner, this episode is your inside look at a summit built for collaboration, clinical excellence, and professional growth.

🔗 Register now at scienceofskinsummit.com

🔔 Subscribe to Science of Skin and leave a review — it helps us bring more cutting-edge dermatology science straight to you.

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Big news for nurse practitioners and physician assistants in dermatology! Dr. Patti Farris is joined by PA and dermatology leader Kristin Rygg to announce a brand-new NP/PA track at the 2026 Science of Skin Summit &mdash; a first-of-its-kind opportunity for advanced practice providers to learn alongside their physician colleagues.
In this episode, you'll hear:
<ul>
<li>Why this NP/PA-dedicated track was created and what makes it different</li>
<li>A full breakdown of the September 10th agenda &mdash; from immunology and inflammatory skin disease to biologics, GLP-1s, and advanced skincare ingredients</li>
<li>How the curriculum is designed for every career stage, from new grads to seasoned practitioners</li>
<li>What to expect at the full Summit (September 17&ndash;20, 2026), including case-based learning, product theaters, and a longevity track</li>
<li>How NPs and PAs will be featured on the main stage for the first time</li>
</ul>
Whether you're a PA, NP, dermatologist, or practice owner, this episode is your inside look at a summit built for collaboration, clinical excellence, and professional growth.
🔗 Register now at <a href="https://scienceofskinsummit.com/">scienceofskinsummit.com</a>
🔔 Subscribe to&nbsp;Science of Skin and leave a review &mdash; it helps us bring more cutting-edge dermatology science straight to you.
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

NP & PA Dermatology Track Debuts at Science of Skin Summit

Did you know your skin has its own internal clock — and that ignoring it could be accelerating aging? In this episode of the Science of Skin podcast, board-certified dermatologist Dr. Patti Farris sits down with renowned cosmetic dermatologist and Harvard graduate Dr. Ava Shamban — founder of AvaMD Dermatology and the skincare line Althea — to break down the fascinating science of circadian rhythms and skin health.

They cover:
What circadian rhythms actually are and why every skin cell has its own biological clock
How clock genes control 50% of your genome — and drive collagen production, DNA repair, and barrier function
Why screen time, blue light, and night-shift schedules are silently destroying your skin
The emerging field of chrono cosmetics — syncing your skincare routine to your skin's natural 24-hour cycle
Dr. Ava's science-backed skincare line Althea and its groundbreaking day/night formulations
Her new multimodal at-home device featuring LED therapy, radio frequency, and microcurrent — pending FDA clearance

Whether you're a skincare enthusiast or a medical professional, this episode will completely change how you think about anti-aging, skin longevity, and your nighttime skincare routine.

🔔 Subscribe to Science of Skin and leave a review — it helps us bring more cutting-edge dermatology science straight to you.

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Did you know your skin has its own internal clock &mdash; and that ignoring it could be accelerating aging? In this episode of the Science of Skin podcast, board-certified dermatologist Dr. Patti Farris sits down with renowned cosmetic dermatologist and Harvard graduate Dr. Ava Shamban &mdash; founder of AvaMD Dermatology and the skincare line Althea &mdash; to break down the fascinating science of circadian rhythms and skin health.
They cover:
<ul>
<li>What circadian rhythms actually are and why every skin cell has its own biological clock</li>
<li>How clock genes control 50% of your genome &mdash; and drive collagen production, DNA repair, and barrier function</li>
<li>Why screen time, blue light, and night-shift schedules are silently destroying your skin</li>
<li>The emerging field of chrono cosmetics &mdash; syncing your skincare routine to your skin's natural 24-hour cycle</li>
<li>Dr. Ava's science-backed skincare line Althea and its groundbreaking day/night formulations</li>
<li>Her new multimodal at-home device featuring LED therapy, radio frequency, and microcurrent &mdash; pending FDA clearance</li>
</ul>
Whether you're a skincare enthusiast or a medical professional, this episode will completely change how you think about anti-aging, skin longevity, and your nighttime skincare routine.
🔔 Subscribe to Science of Skin and leave a review &mdash; it helps us bring more cutting-edge dermatology science straight to you.
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Your Skin Has a Clock: Circadian Rhythms, Aging & Chrono Skincare

What does longevity medicine have to do with your skin? Everything, according to Dr. Hillary Lin — Stanford-trained internist, longevity expert, and founder of CareCorps. In this episode of the Science of Skin podcast, Dr. Patti Farris sits down with Dr. Lin to explore the powerful connection between systemic health and skin aging.

Together they break down the science behind cellular senescence, oxidative stress, and the hallmarks of aging — and what they mean for your skin from the inside out. They cut through the noise on trending anti-aging supplements like rapamycin, NAD precursors, urolithin A, peptides, and creatine, separating evidence-backed strategies from longevity washing. Dr. Lin also shares her expert take on hormone replacement therapy (HRT) and estrogen's critical role in collagen production, skin hydration, and elasticity during perimenopause and menopause.

Whether you're a skincare professional or a health-conscious consumer, this episode delivers practical, science-first insights on skin longevity, metabolic health, and how to build a longevity protocol that actually works.

Topics covered: skin aging, longevity medicine, HRT, perimenopause, collagen, cellular senescence, rapamycin, NAD, creatine, peptides, anti-aging supplements, menopause skin care, hormonal health, longevity washing

To watch this and other episodes, be sure to check out our YouTube page 

DISCLAIMER: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

What does longevity medicine have to do with your skin? Everything, according to Dr. Hillary Lin &mdash; Stanford-trained internist, longevity expert, and founder of CareCorps. In this episode of the Science of Skin podcast, Dr. Patti Farris sits down with Dr. Lin to explore the powerful connection between systemic health and skin aging.
Together they break down the science behind cellular senescence, oxidative stress, and the hallmarks of aging &mdash; and what they mean for your skin from the inside out. They cut through the noise on trending anti-aging supplements like rapamycin, NAD precursors, urolithin A, peptides, and creatine, separating evidence-backed strategies from longevity washing. Dr. Lin also shares her expert take on hormone replacement therapy (HRT) and estrogen's critical role in collagen production, skin hydration, and elasticity during perimenopause and menopause.
Whether you're a skincare professional or a health-conscious consumer, this episode delivers practical, science-first insights on skin longevity, metabolic health, and how to build a longevity protocol that actually works.
Topics covered: skin aging, longevity medicine, HRT, perimenopause, collagen, cellular senescence, rapamycin, NAD, creatine, peptides, anti-aging supplements, menopause skin care, hormonal health, longevity washing
To watch this and other episodes, be sure to check out our&nbsp;<a href="https://www.youtube.com/@scienceofskinpodcast">YouTube</a> page&nbsp;
DISCLAIMER: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

Skin Longevity, HRT & Anti-Aging Science with Dr. Hillary Lin

The Science of Skin is a podcast for those who want to be in-the-know about what's trending in topical skincare and learn about new therapies that are shaping the future of dermatologic care.

Hosts  Dr. Patti Farris and Dr. Ted Lain are board certified dermatologist, recognized experts in topical skincare and co-founders of the Science of Skin Summit. In each episode, The Science of Skin will give you an insider’s view of the skincare industry.  You will hear from research scientists, formulators, and leading physician experts on how products are developed, tested, and used to treat medical and cosmetic patients.  

So, if you’re interested in a behind the scenes look at what makes the skincare industry tick, subscribe to The Science of Skin today. Thanks for listening!

You can also find us on YouTube: https://www.youtube.com/@scienceofskinpodcast

Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

The Science of Skin is a podcast for those who want to be in-the-know about what's trending in topical skincare and learn about new therapies that are shaping the future of dermatologic care.
Hosts &nbsp;Dr. Patti Farris and Dr. Ted Lain are board certified dermatologist, recognized experts in topical skincare and co-founders of the <a href="https://scienceofskincaresummit.com/">Science of Skin Summit</a>. In each episode, The Science of Skin will give you an insider&rsquo;s view of the skincare industry.&nbsp; You will hear from research scientists, formulators, and leading physician experts on how products are developed, tested, and used to treat medical and cosmetic patients. &nbsp;
So, if you&rsquo;re interested in a behind the scenes look at what makes the skincare industry tick, subscribe to The Science of Skin today. Thanks for listening!
You can also find us on YouTube: <a href="https://www.youtube.com/@scienceofskinpodcast">https://www.youtube.com/@scienceofskinpodcast</a>
Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

The Science of Skin

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