Did you know women are twice as likely to develop Alzheimer's disease as men, and oestrogen may be a key reason why? In this episode, Dr Lucy Burns and Dr Mary Barson break down the real science behind oestrogen's role in brain health and dementia prevention, why the infamous 2003 WHI study sent doctors running scared for decades, and what the latest evidence actually means for women in midlife. If MHT is not right for you, don't worry, protecting your brain is never a one-trick pony. This is the episode every woman in midlife needs to hear. 

Research mentioned in this episode: 

• Paganini-Hill A, Henderson VW. Archives of Internal Medicine. 1996 
• Kim YJ et al. Alzheimer's & Dementia. 2021 
• Nerattini M et al. Frontiers in Aging Neuroscience. 2023 
• Cipriano GL et al. International Journal of Molecular Sciences. 2024 
• Melville NA et al. The Lancet Healthy Longevity. 2025 

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Episode, show notes & transcript
https://www.rlmedicine.com/can-hrt-prevent-dementia