Rare Disorders Digest
Rare Disorders Digest
Rare Disorders Digest is a Takeda podcast series designed to inform the audience about different rare diseases, and help them understand current diagnostic and treatment modalities, and some of the challenges that clinicians and patients face today. Listeners will hear from medical experts and patient advocates as they share their insights into current care and describe their aspirations for the …Social links:
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Episode 3 – Clinical experience and challenges with treating post-transplant CMV infection
We head to the clinic this week to hear about Prof. Joe Sasadeusz’s clinical experiences with treating CMV, and the common challenges faced when managing patients with CMV infections. Learn about considerations when selecting between prophylactic and preemptive therapy for patients with CMV infecti…
09:14
Episode 2 – Diagnosis and Treatment of Post-Transplant CMV infection
We chat with Prof. Joe Sasadeusz about current and upcoming approaches to diagnose and treat CMV infections. Prof. Sasadeusz also shares his thoughts on the strengths and limitations of current prophylactic and preemptive treatment strategies and gives us a glimpse into the future of CMV treatment.
06:15
Episode 1 - Living with a lifelong Cytomegalovirus (CMV) infection
CMV is a common and yet permanent infection that poses risks to people with weakened immune systems. In this episode, Prof. Joe Sasadeusz sets the scene by giving an overview of these infections alongside patient advocate, Ms Lisa Foster. CMV infections have serious consequences, especially those …
08:20
Episode 4 – Case Studies
In the last episode of this series on DS and LGS, Prof. Rima Nabbout shares details on several clinical cases involving DS and LGS and outlines her thought process when addressing some of the challenges associated with the diagnosis and management of these conditions in real-world settings.
16:31
Episode 3 – Diagnosis and treatment of LGS
In this episode, Prof. Rima Nabbout describes the clinical presentation, and diagnosis of LGS. She also walks us through some of the available treatment modalities and the limitations associated with treating patients with this disease.
12:19
Episode 2 – Diagnosis and treatment of DS
Prof. Rima Nabbout deep dives into the aetiology of DS, including genetic alterations such as SCN1A mutations. She also tells us about diagnosing and treating these conditions, in addition to some of the challenges she encounters in clinical practice.
14:14
Episode 1 – Living with Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS)
Prof. Rima Nabbout and patient advocate, Ms Lisa Foster, tell us more about DS and LGS, rare epileptic disorders that are associated with high morbidity and mortality, and the significant impact they have on patients and their families.
13:33
Episode 4 – Case Studies
In the last episode of this series on TTP, Dr Eng Soo Yap shares some of his clinical experiences with the diagnosis and management of immune-mediated and congenital forms of TTP.
08:03
Episode 3 – Treatment of TTP
Dr Eng Soo Yap helps us understand more about the role of therapeutic plasma exchange (TPE) in treating iTTP and cTTP, and some of the challenges associated with the current treatment paradigm. He also shares insights on promising therapeutics such as TAK-755 that are currently under investigation.
04:06
Episode 2 – Diagnosis of TTP
Despite extensive research in this area, TTP diagnosis continues to be a challenging affair for clinicians. Dr Eng Soo Yap helps us understand more about the current approach to diagnosis, the importance of ADAMTS13 testing, and the challenges associated with distinguishing between iTTP and cTTP.
03:17