The Department of Justice and the Federal Trade Commission have taken an invigorated approach to antitrust under the Biden administration, targeting companies for labor issues like non-competes, in addition to looking at more traditional measures of anti-competitive behavior, like higher pricing. But how does an economist examine the impact of monopoly practices on the overall economy, or take into account new and different measures of their effects? In this episode, we speak with Ioana Marinescu, principle economist at the DOJ's Antitrust Division, about how she analyzes these thorny issues and what she's learned from specific recent cases, like Activision/Overwatch League, or Penguin Random House’s attempted acquisition of Simon & Schuster.