For more than four decades, Jeffrey Sachs has been a leading voice in global economics and advising governments from Bolivia and Poland to Russia, China, and India. A Harvard graduate with three economics degrees, Sachs became a tenured Harvard professor at just 28 and spent more than two decades teaching at the university before joining Columbia University, where he now serves as University Professor and Director of the Center for Sustainable Development. Sachs has served as a special advisor to three United Nations Secretaries-General, helped launch the Global Fund to Fight AIDS, Tuberculosis and Malaria, and played a pivotal role in shaping the UN Sustainable Development Goals. He is also the author of more than a dozen books, including the New York Times bestseller The End of Poverty. In recent years, Sachs has emerged as one of the most outspoken critics of American foreign policy. In this wide-ranging conversation, he reflects on his extraordinary career, the evolution of American politics and global leadership, and how the United States' role in the world has changed since he first entered the international stage.