When Monica Coenraads’ daughter was diagnosed with Rett syndrome, she refused to accept that nothing could be done. As founder and CEO of the Rett Syndrome Research Trust, she has helped advance groundbreaking research aimed at treating the disorder at its genetic root. In this episode of Get Real, Monica joins Jim Weiss to discuss the personal journey that led her into rare disease advocacy, the promise of gene therapy, and what it takes to turn urgency, hope, and determination into scientific progress. This is a conversation about resilience, purpose, and the power of one family’s fight to change the future for thousands of others.

When Monica Coenraads&rsquo; daughter was diagnosed with Rett syndrome, she refused to accept that nothing could be done. As founder and CEO of the Rett Syndrome Research Trust, she has helped advance groundbreaking research aimed at treating the disorder at its genetic root. In this episode of Get Real, Monica joins Jim Weiss to discuss the personal journey that led her into rare disease advocacy, the promise of gene therapy, and what it takes to turn urgency, hope, and determination into scientific progress. This is a conversation about resilience, purpose, and the power of one family&rsquo;s fight to change the future for thousands of others.

As the founder of internationally acclaimed global health innovation company Real Chemistry, Jim Weiss knows that the key to success and leveraging one's mission is connection -- so he's reached out to innovators in and outside of healthcare to discuss what's now and what's next. He's interviewing world-renowned scientists, CEOs, public health experts, and the list goes on! It's time to GET REAL about the future of healthcare and how to be better health citizens.

Get Real with Jim Weiss

A Mother’s Mission to Cure Rett Syndrome with Monica Coenraads

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/72f0bc87-d479-4a7a-a5e5-b48e01192700/transcript

From helping build one of the world's leading oncology businesses to serving as CEO of a Fortune 500 company, Frank Clyburn has spent his career at the intersection of healthcare, leadership, and innovation. His work helped shape the commercialization of breakthrough medicines, including advances that transformed cancer care. In this episode of Get Real, Frank joins Jim Weiss to discuss the lessons that shaped him, the importance of putting patients first, and how leaders can balance innovation, access, and business success. This is a conversation about resilience, opportunity, and creating lasting impact.

From helping build one of the world's leading oncology businesses to serving as CEO of a Fortune 500 company, Frank Clyburn has spent his career at the intersection of healthcare, leadership, and innovation. His work helped shape the commercialization of breakthrough medicines, including advances that transformed cancer care. In this episode of Get Real, Frank joins Jim Weiss to discuss the lessons that shaped him, the importance of putting patients first, and how leaders can balance innovation, access, and business success. This is a conversation about resilience, opportunity, and creating lasting impact.

Frank Clyburn on Building Great Healthcare Companies

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/634d0472-31d1-4e1a-b24d-b4aa004538f9/transcript

For more than two decades, Dr. Richard Pazdur helped shape the future of cancer treatment from inside the FDA, overseeing many of the therapies that transformed care for patients around the world. He played a central role in building the FDA's oncology review programs and accelerating access to groundbreaking medicines. In this episode of Get Real, Dr. Pazdur joins Jim Weiss to discuss the evolution of cancer care, the challenge of balancing speed with safety, and what it takes to bring lifesaving treatments from the lab to patients. They also explore the future of oncology, global innovation, and why there is still reason for optimism in the fight against cancer.

For more than two decades, Dr. Richard Pazdur helped shape the future of cancer treatment from inside the FDA, overseeing many of the therapies that transformed care for patients around the world. He played a central role in building the FDA's oncology review programs and accelerating access to groundbreaking medicines. In this episode of Get Real, Dr. Pazdur joins Jim Weiss to discuss the evolution of cancer care, the challenge of balancing speed with safety, and what it takes to bring lifesaving treatments from the lab to patients. They also explore the future of oncology, global innovation, and why there is still reason for optimism in the fight against cancer.

Dr. Richard Pazdur on the Future of Cancer Treatment

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/b0dfde0b-878f-4076-a41d-b4a101300f7d/transcript

Robin Carhart-Harris is one of the world's leading researchers studying psychedelics, consciousness, and mental health. For decades, psychedelics sat on the fringes of medicine. Today, they're at the center of some of the most promising research into depression, well-being, and the human mind. Robin's groundbreaking work has helped uncover how substances like psilocybin and LSD affect the brain and their potential role in treating mental illness. Robin joins Jim to explore the science behind psychedelics, what brain imaging studies reveal about consciousness, and why researchers are rethinking the treatment of depression and other mental health conditions. They discuss the role of set and setting, the differences between clinical and non-clinical use, and what the future may hold for psychedelic medicine.

Robin Carhart-Harris is one of the world's leading researchers studying psychedelics, consciousness, and mental health. For decades, psychedelics sat on the fringes of medicine. Today, they're at the center of some of the most promising research into depression, well-being, and the human mind. Robin's groundbreaking work has helped uncover how substances like psilocybin and LSD affect the brain and their potential role in treating mental illness. Robin joins Jim to explore the science behind psychedelics, what brain imaging studies reveal about consciousness, and why researchers are rethinking the treatment of depression and other mental health conditions. They discuss the role of set and setting, the differences between clinical and non-clinical use, and what the future may hold for psychedelic medicine.

The Science of Psychedelics with Robin Carhart Harris

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/88e32ff6-86d7-4569-8ce2-b49c0024e53d/transcript

A Mother’s Mission to Cure Rett Syndrome with Monica Coenraads

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