The ultimate outcome for patients who are resuscitated from cardiac arrest depends heavily on the neurological damage that results from a low flow state.  Prevention of further damage during this phase is one of the core goals of post resuscitation care.

In recent years, a multitude of research papers have been produced which examine various aspects of this approach, including oxygenation and blood pressure targets. 

One alternative strategy may be to increase cerebral blood flow by allowing mild therapeutic hypercapnoea, an approach studied in the recently released TAME trial.  Principle investigator of the study, Glenn Eastwood, joins Todd on the podcast to discuss the key features and results from this important trial.