TAME

The ultimate outcome for patients who are resuscitated from cardiac arrest depends heavily on the neurological damage that results from a low flow state.  Prevention of further damage during this phase is one of the core goals of post resuscitation care. In recent years, a multitude of research pa…

Dexmedetomidine for NIV

Non invasive ventilation is steadily establishing itself as a crucial component of the critical care armoury.  While many patients can tolerate it, some require sedation. Wisam Al-Bassam is a staff specialist at Monash Medical center and Victorian Heart hospital.  Wisam is passionate about educati…

DIC

This podcast comes to you from the 2022 LIVES Conference in Paris Disseminiated intravascular coagulation is the endpoint of a range of different conditions, including sepsis.  How does this important clinical condition evolve, and what can we do about it? Mirjam Bachler is a senior post doc rese…

Logical

Cardiac arrest causes neurological injury through a sustained period of hypoxia and ischaemia.  It has long been thought that avoiding further hypoxia could save vulnerable brain tissue, leading to the common practice of deliberate hyperoxygenation. However, recent research has suggested this appr…

Driving pressures in Acute respiratory failure

This podcast comes to you from the 25th Annual Noosa meeting of the ANZICS Clinical Trials Group. It is now well recognised that mechanical ventilation, while potentially lifesaving, also causes damage to the lung in its own right.  Careful setting of the ventilator is crucial to avoiding lung inj…

Trauma Induced Coagulopathy

Managing bleeding in a patient with severe trauma is a complex process, with multiple interventions occurring in parallel. Derek Kleinveld is an anesthesiology resident at the Erasmus MC in Rotterdam, The Netherlands, and a post-doc researcher with an interest in Trauma Induced Coagulopathy.  He j…

Ventilation in TBI

In traumatic brain injury, the lung and the brain are caught in a complex interplay, where the challenges of managing one can affect the other. Chiara Robba is a consultant in Neuro and General Intensive Care at Policlinico San Martino, Genova.  She has a PhD in neuroscience and is the current cha…

Patient induced lung injury

Ventilation is known to cause injury to the lungs in its own right, but now it is becoming clear that the respiratory effort of the patient may also contribute to ongoing pulmonary damage. Antonio Pesenti joins Todd to discuss what we know, and the future of research in this area.

CLIP-2 part 2

Part 2 of this interview with CLIP-2 chief investigator Michael Reade explores the structure of CLIP-2, some of the challenges the project has had to overcome, and the workings of a non-inferiority trial.

CLIP-2 part 1

Platelets are a critical component of haemostatic resuscitation, but there are significant challenges involved in their use, most notably, their short shelf life. Could frozen platelets be the answer? Michael Reade is an anaesthetist, intensivist and clinical researcher from the University of Que…