TAME

The ultimate outcome for patients who are resuscitated from cardiac arrest depends heavily on the neurological damage that results from a low flow state.  Prevention of further damage during this phase is one of the core goals of post resuscitation care. In recent years, a multitude of research pa…

eCPR and the SHERPA trial

This podcast comes to you from the 2023 ANZICS Clinical Trials Group Noosa meeting. ECMO (extracorporeal membrane oxygenation) is steadily embedding itself into modern critical care medicine.   Does it have a role in pre-hospital setting for patients with refractory cardiac arrest? In this podca…

Dexmedetomidine for NIV

Non invasive ventilation is steadily establishing itself as a crucial component of the critical care armoury.  While many patients can tolerate it, some require sedation. Wisam Al-Bassam is a staff specialist at Monash Medical center and Victorian Heart hospital.  Wisam is passionate about educati…

Respiratory muscle training after ICU

This podcast comes from the 25th annual Noosa meeting of the ANZICS Clinical Trials Group. Prolonged ventilation leaves critically ill patients at risk of a number of complications, including persistent respiratory muscle weakness. Marc Nickels is a physiotherapist and ICU researcher from the Pri…

Fluids in DKA

DKA causes a serious disturbance of fluid and electrolyte balance. However, it is said that more complications are caused by our management than by the disease itself.  This is no more apparent than in our management of the patient's fluids. Professor Bala Venkatesh is a world renowned intensive …

Logical

Cardiac arrest causes neurological injury through a sustained period of hypoxia and ischaemia.  It has long been thought that avoiding further hypoxia could save vulnerable brain tissue, leading to the common practice of deliberate hyperoxygenation. However, recent research has suggested this appr…

Driving pressures in Acute respiratory failure

This podcast comes to you from the 25th Annual Noosa meeting of the ANZICS Clinical Trials Group. It is now well recognised that mechanical ventilation, while potentially lifesaving, also causes damage to the lung in its own right.  Careful setting of the ventilator is crucial to avoiding lung inj…

TEAM

It is well known that critical illness often features a pro-catabolic state, which can lead to muscle atropy and long term functional deficits.  Early mobilisation has been thought to slow the rate of muscle loss, and potentially improve these outcomes. Professor Carol Hodgson is Head of the Divis…

Thrombolysis in ARDS

The pathophysiology of ARDS is complex and remains incompletely understood.  However, it is clear that ARDS is not simply a disease of the alveoli. Understanding the pathological basis of ARDS will assist in the development of new therapies for this potentially fatal disease. One such avenue is t…

PRECISION-TBI

Traumatic brain injury is a significant problem, affecting patients of all ages across the globe.  Despite this, relatively little hard evidence supports the interventions commonly used in practice. Research in this area remains challenging, with many barriers to the traditional large-scale random…