Discover the revolutionary potential of CAR T-cell therapy as a possible cure for some types of cancer. In this episode, Dr. Diane Reidy-Lagunes speaks with the pioneer of CAR T-cell therapy, MSK immunologist Dr. Michel Sadelain, as well as cellular therapist Dr. Jae Park, about the intricate process of modifying a patient’s own immune cells to target and eliminate cancer cells. They discuss its origin, clinical success in treating blood cancers like lymphoma and leukemia, and potential side effects. Dr. Sadelain addresses cost concerns, proposing strategies to enhance accessibility, while both doctors express optimism for CAR T-cell therapy’s future in treating, and maybe curing, a wider range of cancers, including solid tumors.