Jessa interviews Ben on the bus ride to the start line for Ironman 70.3 Japan.

Jessa interviews Ben on the bus ride to the start line for Ironman 70.3 Japan.

Free fitness, nutrition, biohacking, fat loss, anti-aging and cutting-edge health advice from BenGreenfieldLife.com! Tune in to the latest research, interviews with exercise, diet and medical professionals, and an entertaining mash-up of ancestral wisdom and modern science, along with Q&A's and mind-body-spirit optimizing content from America's top personal trainer.

Boundless Life

Ironman 70.3 Japan Pre-Race Interview

Full show notes: BenGreenfieldLife.com/drtyna

I'm re-airing my conversation with Dr. Tyna Moore about GLP-1s because almost everything she said about them is still being misunderstood, and she was one of the earliest voices advocating for using these drugs at very low doses. When we recorded, the internet had largely decided GLP-1 agonists were terrible: muscle wasting, "Ozempic face," suicidality, and more. Tyna's take was very different, and much of what she discussed has held up surprisingly well. Not everything, though. The big Alzheimer's trials found that GLP-1 treatment did not significantly slow disease progression.

I was the guinea pig for this one. The week before our interview, I injected one-tenth of the standard semaglutide dose, and Dr. Moore told me on air that even that was far too much for me. She was right. It took me three days to get through one porterhouse steak.

You'll hear what dosing for appetite control rather than appetite suppression actually looks like, why a natural GLP-1 stimulator may not do much if the gut cells that release GLP-1 have stopped responding, what the thyroid cancer black box warning is actually based on, what that widely shared suicidality study really measured, and how to protect your muscle while using these drugs. Dr. Tyna Moore also shares where she sends people now that she has stopped taking new patients, which is The Menopause Rebellion, her community for Gen X women covering hormones, metabolism, muscle building, GLP-1s, and peptides.

Episode Sponsors:

ALYA Health: A high-polyphenol, single-origin olive oil made from rare Tunisian Chetoui olives, designed to be taken as a daily shot before a meal. Visit AlyaHealth.com/s/ben or use code BEN for 20% off your first order.

JOYMODE: Want to spice things up in the bedroom, boost your sexual performance, and do it naturally without nasty prescription drugs? Visit tryjoymode.com/BEN or enter BEN at checkout for 20% off your first order of JOYMODE.

ULTRA: A clean, nicotine-free, and caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters or crashes. Visit takeultra.com and use code BENGREENFIELD for 15% off.

Dr. Murray Natural Products – ThymoQuin®: A clinically researched black seed oil that supports healthy cortisol levels and resilience to everyday stress. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products.

Full show notes: <a href="https://bengreenfieldlife.com/drtyna">BenGreenfieldLife.com/drtyna</a>
I'm re-airing my conversation with Dr. Tyna Moore about <a href="https://www.ncbi.nlm.nih.gov/books/NBK551568/">GLP-1s</a> because almost everything she said about them is still being misunderstood, and she was one of the earliest voices advocating for using these drugs at very low doses. When we recorded, the internet had largely decided GLP-1 agonists were terrible: muscle wasting, "Ozempic face," suicidality, and more. Tyna's take was very different, and much of what she discussed has held up surprisingly well. Not everything, though. The big Alzheimer's trials found that GLP-1 treatment did not significantly slow disease progression.
I was the guinea pig for this one. The week before our interview, I injected one-tenth of the standard <a href="https://shoplifemarket.com/">semaglutide</a> dose, and Dr. Moore told me on air that even that was far too much for me. She was right. It took me three days to get through one porterhouse steak.
You'll hear what dosing for appetite control rather than appetite suppression actually looks like, why a natural GLP-1 stimulator may not do much if the gut cells that release GLP-1 have stopped responding, what the thyroid cancer black box warning is actually based on, what that widely shared suicidality study really measured, and how to protect your muscle while using these drugs. <a href="https://www.instagram.com/drtyna/">Dr. Tyna Moore</a> also shares where she sends people now that she has stopped taking new patients, which is <a href="https://www.skool.com/drtyna/about">The Menopause Rebellion</a>, her community for Gen X women covering hormones, metabolism, muscle building, GLP-1s, and peptides.
Episode Sponsors:
<a href="https://alyahealth.com/s/ben">ALYA Health</a>: A high-polyphenol, single-origin olive oil made from rare Tunisian Chetoui olives, designed to be taken as a daily shot before a meal. Visit <a href="https://alyahealth.com/s/ben">AlyaHealth.com/s/ben</a> or use code BEN for 20% off your first order.
<a href="https://usejoymode.com/GREENFIELD">JOYMODE</a>: Want to spice things up in the bedroom, boost your sexual performance, and do it naturally without nasty prescription drugs? Visit <a href="https://tryjoymode.com/BEN">tryjoymode.com/BEN</a> or enter BEN at checkout for 20% off your first order of JOYMODE.
<a href="https://bengreenfieldlife.com/ultra">ULTRA</a>: A clean, nicotine-free, and caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters or crashes. Visit <a href="https://takeultra.com">takeultra.com</a> and use code BENGREENFIELD for 15% off.
<a href="https://doctormurray.com/ben">Dr. Murray Natural Products &ndash; ThymoQuin&reg;</a>: A clinically researched black seed oil that supports healthy cortisol levels and resilience to everyday stress. Visit <a href="https://doctormurray.com/ben">doctormurray.com/ben</a> and use code BEN25 for 25% off all Dr. Murray Natural Products.

How To Microdose GLP-1s Correctly: Lose The Fat, And KEEP The Muscle - With Dr. Tyna Moore

Full show notes:BenGreenfieldLife.com/AGIpodcast

In this episode, you'll hear how artificial intelligence is actually being pointed at aging right now, including an algorithm picking which Chinese herbs extend a fruit fly's life, plus whether the biological age test you just paid for means anything at all.

My guest is Dr. Ben Goertzel, who popularized the term artificial general intelligence, runs a decentralized AI network, and is chief scientist at Hanson Robotics. We get into the long-lived fruit flies his team works on at Genescient, the roughly five traditional Chinese herbs an AI selected from a database and combined in ways that more than double a middle-aged fly's life, and why the AI mixes them in combinations no Chinese medicine practitioner ever would. You'll also learn why he says today's biological age tests are "a little dodgy," why large language models keep handing you the existing literature instead of generating new science, and what the extracellular matrix has to do with whether your whole body is aging well. We close on the engineered enzymes he thinks will eventually re-sculpt the genome of every tissue in your body, my own follistatin gene therapy result, and the band he plays keyboards in with a humanoid robot lead singer.

Episode Sponsors:

Dr. Murray Natural Products – ThymoQuin®: A clinically researched black seed oil formulated to support healthy cortisol levels and resilience to everyday stress. It's the only black seed oil that meets U.S. Pharmacopeia guidelines. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products.

Young Goose: To experience the transformative power of Young Goose's cutting-edge skincare products, visit younggoose.com and use code BGF10 at checkout to enjoy a 10% discount on your order.

ALYA Health: A high-polyphenol, single-origin olive oil made from rare Tunisian Chetoui olives and designed to be taken as a daily shot before a meal. Visit AlyaHealth.com/s/ben or use code BEN for 20% off your first order.

Active Skin Repair: Uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS.

Nuchido: Support healthy aging at the cellular level with Nuchido TIME+, designed to optimize your body's NAD (nicotinamide adenine dinucleotide) metabolism across multiple pathways rather than a single ingredient. Visit BenGreenfieldLife.com/Nuchido and use code BEN20 to save 20% on your order.

Full show notes:<a href="https://bengreenfieldlife.com/AGIpodcast"> </a><a href="https://bengreenfieldlife.com/AGIpodcast">BenGreenfieldLife.com/AGIpodcast</a>
In this episode, you'll hear how artificial intelligence is actually being pointed at aging right now, including an algorithm picking which Chinese herbs extend a fruit fly's life, plus whether the biological age test you just paid for means anything at all.
My guest is<a href="https://x.com/bengoertzel"> Dr. Ben Goertzel</a>, who popularized the term artificial general intelligence, runs a decentralized AI network, and is chief scientist at Hanson Robotics. We get into the long-lived fruit flies his team works on at<a href="https://www.genescient.com/"> Genescient</a>, the roughly five traditional Chinese herbs an AI selected from a database and combined in ways that more than double a middle-aged fly's life, and why the AI mixes them in combinations no Chinese medicine practitioner ever would. You'll also learn why he says today's biological age tests are "a little dodgy," why large language models keep handing you the existing literature instead of generating new science, and what the<a href="https://www.ncbi.nlm.nih.gov/books/NBK26810/"> extracellular matrix</a> has to do with whether your whole body is aging well. We close on the<a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138569"> engineered enzymes</a> he thinks will eventually re-sculpt the genome of every tissue in your body, my own follistatin gene therapy result, and the band he plays keyboards in with a humanoid robot lead singer.
Episode Sponsors:
<a href="https://doctormurray.com/ben">Dr. Murray Natural Products &ndash; ThymoQuin&reg;:</a> A clinically researched black seed oil formulated to support healthy cortisol levels and resilience to everyday stress. It's the only black seed oil that meets U.S. Pharmacopeia guidelines. Visit<a href="https://doctormurray.com/ben"> doctormurray.com/ben</a> and use code BEN25 for 25% off all Dr. Murray Natural Products.
<a href="https://bengreenfieldlife.com/younggoosepodcastads">Young Goose:</a> To experience the transformative power of Young Goose's cutting-edge skincare products, visit<a href="https://bengreenfieldlife.com/younggoosepodcastads"> younggoose.com</a> and use code BGF10 at checkout to enjoy a 10% discount on your order.
<a href="https://alyahealth.com/s/ben">ALYA Health:</a> A high-polyphenol, single-origin olive oil made from rare Tunisian Chetoui olives and designed to be taken as a daily shot before a meal. Visit<a href="https://alyahealth.com/s/ben"> AlyaHealth.com/s/ben</a> or use code BEN for 20% off your first order.
<a href="https://activeskinrepair.com">Active Skin Repair:</a> Uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals. Go to<a href="https://activeskinrepair.com"> ActiveSkinRepair.com</a> and use code BEN for 20% off, or find it on Amazon and at your local CVS.
<a href="https://bengreenfieldlife.com/Nuchido">Nuchido:</a> Support healthy aging at the cellular level with Nuchido TIME+, designed to optimize your body's NAD (nicotinamide adenine dinucleotide) metabolism across multiple pathways rather than a single ingredient. Visit<a href="https://bengreenfieldlife.com/Nuchido"> BenGreenfieldLife.com/Nuchido</a> and use code BEN20 to save 20% on your order.

This Man Thinks "AGI" Could Allow Humans To Live Forever, With Dr. Ben Goertzel

Full show notes: BenGreenfieldLife.com/506

In this episode, you'll discover three things I've been asked about constantly: whether the melatonin heart failure headline is worth worrying about, how much sleep is actually too much or too little, and the shortest route to a higher VO2 max.

I break down what the melatonin study did and did not reveal, why a key prescription detail changes how the findings should be interpreted, and why I still use high-dose melatonin for jet lag. Then I move to VO2 max, including the Norwegian 4x4 explained the way I used to coach it, what the sprint interval research says about doing it faster, and the tools that work beyond exercise, from heat acclimation to altitude to correcting an iron deficiency. You'll also hear what a new Nature study of half a million people found about the 6.4 to 7.8 hour sleep window, and why I still sleep less than that on purpose.

Finally, fertility for men and women. On the male side, scrotal temperature, timing intercourse around ovulation, the lubricant problem nobody mentions, and the supplements with real human data behind them, from L-carnitine and CoQ10 to zinc and shilajit (use code GREENFIELD for free shipping). On the female side, ovulation tracking, acupuncture, CoQ10 before egg retrieval, and inositol. Plus how to preserve fertility if you're on testosterone replacement therapy (TRT).

Episode Sponsors:

BIOptimizers Magnesium Breakthrough Advanced 10: Ten bioavailable forms of magnesium with active vitamin B6 and ionic trace minerals to support uptake, sleep, recovery, stress, and metabolic health. Go to bioptimizers.com/ben and use code BEN15 for 15% off any order.

Timeline: Give your cells new life with Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule. Mitopure now starts at $79 at timeline.com/BEN.

ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters or crashes. Visit takeultra.com and use code BENGREENFIELD for 15% off.

Tiny Health: An at-home microbiome test that analyzes your full gut ecosystem and gives you personalized, evidence-based diet and supplement recommendations. Get $50 off your first kit at TinyHealth.com/BEN.

Active Skin Repair: Uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS.

Full show notes:<a href="https://bengreenfieldlife.com/506"> BenGreenfieldLife.com/506</a>
In this episode, you'll discover three things I've been asked about constantly: whether the<a href="https://newsroom.heart.org/news/long-term-use-of-melatonin-supplements-to-support-sleep-may-have-negative-health-effects"> melatonin heart failure headline</a> is worth worrying about, how much sleep is actually too much or too little, and the shortest route to a higher VO2 max.
I break down what the melatonin study did and did not reveal, why a key prescription detail changes how the findings should be interpreted, and why I still use high-dose melatonin for jet lag. Then I move to VO2 max, including the<a href="https://doi.org/10.1249/mss.0b013e3180304570"> Norwegian 4x4</a> explained the way I used to coach it, what the<a href="https://doi.org/10.1111/sms.70347"> sprint interval research</a> says about doing it faster, and the tools that work beyond exercise, from heat acclimation to altitude to correcting an iron deficiency. You'll also hear what a<a href="https://www.nature.com/articles/s41586-026-10524-5"> new Nature study</a> of half a million people found about the 6.4 to 7.8 hour sleep window, and why I still sleep less than that on purpose.
Finally, fertility for men and women. On the male side, scrotal temperature, timing intercourse around ovulation, the lubricant problem nobody mentions, and the supplements with real human data behind them, from L-carnitine and CoQ10 to zinc and<a href="https://bengreenfieldlife.com/blacklotus"> shilajit</a> (use code GREENFIELD for free shipping). On the female side, ovulation tracking, acupuncture,<a href="https://doi.org/10.1186/s12958-018-0343-0"> CoQ10 before egg retrieval</a>, and inositol. Plus how to preserve fertility if you're on testosterone replacement therapy (TRT).
Episode Sponsors:
<a href="https://bioptimizers.com/ben">BIOptimizers Magnesium Breakthrough Advanced 10</a>: Ten bioavailable forms of magnesium with active vitamin B6 and ionic trace minerals to support uptake, sleep, recovery, stress, and metabolic health. Go to<a href="https://bioptimizers.com/ben"> bioptimizers.com/ben</a> and use code BEN15 for 15% off any order.
<a href="https://timeline.com/ben">Timeline</a>: Give your cells new life with Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule. Mitopure now starts at $79 at<a href="https://timeline.com/BEN"> timeline.com/BEN</a>.
<a href="https://bengreenfieldlife.com/ultra">ULTRA</a>: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters or crashes. Visit<a href="https://takeultra.com"> takeultra.com</a> and use code BENGREENFIELD for 15% off.
<a href="https://tinyhealth.com/BEN">Tiny Health</a>: An at-home microbiome test that analyzes your full gut ecosystem and gives you personalized, evidence-based diet and supplement recommendations. Get $50 off your first kit at<a href="https://tinyhealth.com/BEN"> TinyHealth.com/BEN</a>.
<a href="https://activeskinrepair.com">Active Skin Repair</a>: Uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals. Go to<a href="https://activeskinrepair.com"> ActiveSkinRepair.com</a> and use code BEN for 20% off, or find it on Amazon and at your local CVS.

How To Increase Fertility (For Males & Females!), How Much Sleep Is Too Much (Or Too Little)? & A "Minimalist" Approach To Increasing VO2 Max! Solosode #506

Ironman 70.3 Japan Pre-Race Interview

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