Full show notes: bengreenfieldlife.com/braindefenders

In this episode, board-certified neurologist Dr. David Perlmutter joins me to talk through his new book, Brain Defenders, and his case that the beta-amyloid drugs for Alzheimer’s (drugs that target a sticky brain protein) haven’t delivered the results many hoped for. You’ll discover how microglia, your brain’s own immune cells, can protect your neurons or damage them, and what may tip them in either direction. You’ll also learn why the metabolism of those cells may mirror the metabolism of your whole body, which could put more of your brain’s future in your hands than you might expect.

David and I also dig into the gut-brain link, from ultra-processed food to fecal transplants, the blood tests he recommends, and how herbicides like glyphosate and paraquat, as well as wildfire smoke, may affect your brain. You’ll learn about duckweed, minocycline, and RNS60, a nanobubble saline being studied in stroke and amyotrophic lateral sclerosis (ALS), what the glucagon-like peptide-1 (GLP-1) trials in Parkinson’s and Alzheimer’s reported, my own accidental retatrutide injection, and the lifestyle trial that reported improvements in early Alzheimer’s after 20 weeks without using any drugs.

You can find his new book, Brain Defenders, here.

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