In this 109th episode of the Soberhead Podcast Dr. Esra Çavuşoğlu, PhD welcomes Dr. Felice Gersh, MD.

Dr. Felice Gersh is a board-certified obstetrician-gynecologist and also a specialist in integrative medicine. She focuses on women’s hormones, PCOS, menopause, and the gut-hormone connection. Dr. Gersh is known for her holistic approach, combining modern medicine with nutrition and lifestyle strategies.

Dr. Gersh mentions that menopause should be viewed not just as a hormone deficiency, but as a loss of rhythms specifically circadian and lunar, menstrual cycles.

She challenges the "less is best" mantra of conventional medicine, explaining how low-dose, static hormone regimens may fail to provide the growth factors necessary for mitochondrial health and neuroprotection.

The conversation dives deep into the "metabolic jet lag" of menopause and the critical need for cyclic progesterone. Dr. Gersh explains why oral progesterone can be problematic due to high conversion into allopregnanolone (a sedative metabolite) and why "physiological" levels of estradiol often higher than what is standardly prescribed are vital for healthy longevity.

#EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab #DrFeliceGersh

Special thanks to T.C. Istanbul Gedik University https://www.gedik.edu.tr/en/

Dr. Felice Gersh, MD Website: https://integrativemgi.com/about-dr-felice-gersh/
Instagram: https://www.instagram.com/dr.felicegersh/


00:00-05:02 Introduction to Dr. Felice Gersh
05:02-07:25 The link between circadian rhythms and organ function
07:25-18:57 Testosterone for Women: Sources (adrenals vs. ovaries) and why levels drop by age 40.
18:57-20:08 Individualizing Testosterone: Finding the "edge" without virilization.
20:08-23:07 PCOS & Leadership: The natural advantage of slightly higher androgens
23:07-27:40 The Case for Cyclic Progesterone
27:40-36:18 Growth Factors & Estrogen: Restoring mitochondrial function and tissue health
36:18-39:12 Effect of Oral Estrogen on the Liver
39:12-41:34 The Oral Progesterone Problem
41:34-48:41 Alternative Routes: Vaginal vs. Rectal progesterone for better absorption
48:41-53:10 Optimal Estradiol Levels
53:10-1:00:11 Tolerating Higher Estrogen: Using "two-dose" strategies to mimic a real cycle
1:00:11-1:09:13 *Progesterone’s Hidden Benefits: Bone health, myelin insulation, and anti-inflammation
1:09:13-1:12:12 Wrap up.

*About Ayık Kafa* Dr. Esra Çavuşoğlu, PhD, took her studies, starting from her personal treatment experiences and continuing with her clinical psychology education, to the next level by completing her PhD focused on Addiction. Dr. Esra in Ayık Kafa podcast discusses the world’s latest technologies, protocols, products and research in the fields of Biohacking and Longevity, while sharing first-hand information and experiences about the Disease of Addiction, as well as her latest academic studies.

*About Dr. Esra Çavuşoğlu, PhD* Longevilab’s founder, Dr. Esra, is a United States and internationally trained clinical psychologist and a certified addiction therapist in New York. She served as International Development Advisor on the Yale University Faculty of Medicine Clinical Advisory Board. She is the founder and supervisor of Gaziantep Oya Bahadır Yüksel Rehabilitation Center, Dr. Esra is the designer and implementer of the Turkey Rehabilitation Model. Dr. Esra founded the Contemporary Addiction Studies Association (ÇABAÇAD) in order to combat Turkey’s growing addiction problem.

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