In this 123rd episode of Sober Head Podcast, Dr. Esra Çavuşoğlu, PhD welcomes Prof. Brian Kennedy. In this episode, leading geroscientist Prof. Brian Kennedy explains how longevity science can move beyond academic laboratories and into responsible, real-world clinical practice. We explore mTOR and rapamycin, CA-AKG, biological age testing, ovarian aging, menopause-delaying research, peptides, gene therapies, and the growing longevity clinic industry.

Dr. Kennedy warns that combining too many supplements may unintentionally over-suppress essential cellular pathways. He also explains why many commercial biological age tests remain inconsistent, why personalized measurement matters, and how peptides could become some of the most important longevity medicines of the future.

We also discuss Singapore’s $300 million healthy longevity initiative and why healthcare must shift from treating disease to preserving health and performance throughout life.

#EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab #BrianKennedy
Prof. Brian Kennedy
Website: https://medicine.nus.edu.sg/sites/briankennedylab/?utm_source=chatgpt.com
https://www.prolon.com.tr/*10% off throughout August with the code AYIKKAFA10.
Special thanks to T.C. Istanbul Gedik University https://www.gedik.edu.tr/en/

00:00-03:23 Introduction to Prof. Brian Kennedy
03:23-06:05 Why billionaires became the new research model
06:05-13:16 Rapamycin, mTOR and the risks of supplement stacking
13:16-17:44 Can menopause be delayed?
17:44-19:17 Moving from animal models to human trials
19:17-24:20 Ca-AKG, NAD and Urolithin A
24:20-29:09 Why biological age tests may be unreliable
29:09-33:22 Living to 150 and longevity escape velocity
33:22-37:04 Gene therapy, cellular reprogramming and organ replacement
37:04-43:23 Preventive healthcare, lifestyle and the alcohol debate
43:23-51:02 Singapore’s $300 million longevity initiative
51:02-55:00 Longevity clinics, peptides and future therapies
55:00-58:00 Do health and enjoyment have to conflict?
58:00-1:01:46 Wrap up.

*About Ayık Kafa* Dr. Esra Çavuşoğlu, PhD, took her studies, starting from her personal treatment experiences and continuing with her clinical psychology education, to the next level by completing her PhD focused on Addiction. Dr. Esra in Ayık Kafa podcast discusses the world’s latest technologies, protocols, products and research in the fields of Biohacking and Longevity, while sharing first-hand information and experiences about the Disease of Addiction, as well as her latest academic studies.

*About Dr. Esra Çavuşoğlu, PhD* Longevilab’s founder, Dr. Esra, is a United States and internationally trained clinical psychologist and a certified addiction therapist in New York. She served as International Development Advisor on the Yale University Faculty of Medicine Clinical Advisory Board. She is the founder and supervisor of Gaziantep Oya Bahadır Yüksel Rehabilitation Center, Dr. Esra is the designer and implementer of the Turkey Rehabilitation Model. Dr. Esra founded the Contemporary Addiction Studies Association (ÇABAÇAD) in order to combat Turkey’s growing addiction problem.

DisclaimerThe information and statements on our YouTube Channel Sober-Head are not intended to guide individuals towards medical diagnosis and treatment.Please consult with your doctor for medical diagnostic and treatment procedures.The content is shared for informational purposes only, derived from scientific studies prepared by EMC Medya Yayıncılık Ticaret Ltd. Şti.’s researchers, consultants, and authors/scientists, as well as compilations from publicly available public