Drug resistance is a major challenge in oncology and genetically-engineered mouse models represent powerful tools to identify new approaches for its overcoming.

In this TJ Talks podcast, Prof Paola Perego, Pharmacology Section Editor of Tumori Journal and Adjunct Professor at the University of Insubria, talks with Professor Sven Rottenberg, head of the Institute of Animal Pathology at the University of Bern, about drug resistance and the reasons why it is so difficult to eradicate tumors during treatment.