The field of bioinformatics is rapidly evolving, shaping the future of biomedical research and precision medicine. From cutting-edge advancements in computational biology to AI-driven solutions, what will the landscape look like in Italy in the coming years, and what opportunities will emerge for young bioinformaticians?In this TJ Talks event, the Bioinformatics Section Editor of Tumori Journal, Prof. Lorenzo Ferrando - Research Associate of Applied Medical Technology and Sciences, Department of Internal Medicine, University of Genoa - guides us through a discussion on the key trends and career prospects in bioinformatics. Joining him is Prof. Matteo Benelli, Associate Professor of Biochemistry at the University of Florence and Co-Principal Investigator of AURORA, an international research program dedicated to uncovering the molecular mechanisms driving therapy response and resistance in recurrent metastatic breast cancer.