This Pathological LifeEp 20 Helicobacter pylori | The No Acid No Ulcer Fallacy
** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode **
In 1983, Dr Robin Warren and Dr Barry Marshall embarked upon a study to investigate the significance of bacterial found in the stomachs of ulcer patients. This journey would take them over a decade to complete and was riddled with self-doubt, persistent scepticism, and challenging centuries of medical dogma but their persistence ultimately led to the highest accolade in Medicine.
Oh, and a bout of bad breath.
Helicobacter pylori is a gram-negative bacteria that has evolved with humans. With an estimated worldwide prevalence of up to 50%, this organism has found a survival niche where it is perfectly suited to thrive in the stomach’s highly acidic environment. Unfortunately for those of us who have it, it will cause inflammation (gastritis) but can eventually lead to cancer (gastric adenocarcinoma).
Our interview is with Professor Barry Marshall who navigates the lows of persistent knockbacks through to the worldwide tour that lead to the Nobel Prize in 2005.
Professor Barry Marshall
Nobel Prize Laureate and Professor of Clinical MicrobiologyThe discovery by Dr Warren and Professor Marshall has benefited millions of people, maybe saving a million lives over the last 10 or 20 years.
Barry James Marshall AC FRACP FRS FAA is an Australian physician, Nobel Prize Laureate in Physiology or Medicine, and Professor of Clinical Microbiology at the University of Western Australia. https://www.uwa.edu.au/profile/barry-marshall
Additional links of interest:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)67587-3/fulltext
