In August 1968, a rather innocuous letter to the editor was published in the New England Journal of Medicine.



Dr Ho Man Kwok had written in speculating on the reason he felt so ghastly after eating at a Chinese restaurant. Was it the soy sauce or the cooking wine? Or perhaps, he offered up, it was the monosodium glutamate seasoning - MSG.



The prominent symptoms, as he described them, were numbness at the back of his neck, general weakness and heart palpitations.



Surely Dr Kwok hadn’t just overeaten or sampled a few too many beverages during the evening. There must be another explanation and something else to blame.



The New England Journal, which clearly did a lot of background checking, thorough research and fact-finding *ahem* decided to run with this madness and the term “Chinese Restaurant Syndrome” was coined.



And so, the flurry of MSG bad-mouthing and hysteria took off.



Now, more than five decades later surveys suggest that a whopping 43% of Americans believe that MSG is bad for you. And we wouldn’t be surprised if Australia fell in line with this statistic.



The “syndrome” has exploded to encompass symptoms far beyond Dr Kwok’s initial complaint. People report muscle tightening, burning sensations, and almost fainting. And, most notably, an irresistible urge to take off all your clothes.



We can certainly blame MSG for that... 



But is this all bollocks? Are there any real studies from the whole of science that prove or disprove these theories? After a few sprinkles of MSG in their beer, Will takes Rod on a journey through racism, hysteria and deliciousness all in the name of acquitting MSG in the court of public opinion.



Previous Episodes Mentioned:

Musical Maladies - And Fakes!



Sources
Jennifer LeMesurier’s Poroi (An Interdisciplinary Journal of Rhetorical Analysis and Invention) article: Uptaking Race: Genre, MSG, and Chinese Dinner
Ian Mosby’s: ‘That Won-Ton Soup Headache’: The Chinese Restaurant Syndrome, MSG and the Making of American Food, 1968–1980
Michael Blanding’s article in Colgate Magazine: The Strange Case of Dr Ho Man Kwok
Richard D Lyons article in the New York Times: ‘Chinese Restaurant Syndrome’ Puzzles Doctors. May 19 1968
Herbert Schaumburg and Robert Byck’s article in Science: Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome
This American Life’s The Long Fuse
The Washington Post’s: Beware of musher's knee and hooker's elbow
Umami Information Center: Kikunae Ikeda

In August 1968, a rather innocuous letter to the editor was published in the New England Journal of Medicine.
 
Dr Ho Man Kwok had written in speculating on the reason he felt so ghastly after eating at a Chinese restaurant. Was it the soy sauce or the cooking wine? Or perhaps, he offered up, it was the monosodium glutamate seasoning - MSG.
 
The prominent symptoms, as he described them, were numbness at the back of his neck, general weakness and heart palpitations.
 
Surely Dr Kwok hadn’t just overeaten or sampled a few too many beverages during the evening. There must be another explanation and something else to blame.
 
The New England Journal, which clearly did a lot of background checking, thorough research and fact-finding *ahem* decided to run with this madness and the term “Chinese Restaurant Syndrome” was coined.
 
And so, the flurry of MSG bad-mouthing and hysteria took off.
 
Now, more than five decades later surveys suggest that a whopping 43% of Americans believe that MSG is bad for you. And we wouldn’t be surprised if Australia fell in line with this statistic.
 
The “syndrome” has exploded to encompass symptoms far beyond Dr Kwok’s initial complaint. People report muscle tightening, burning sensations, and almost fainting. And, most notably, an irresistible urge to take off all your clothes.
 
We can certainly blame MSG for that... 
 
But is this all bollocks? Are there any real studies from the whole of science that prove or disprove these theories? After a few sprinkles of MSG in their beer, Will takes Rod on a journey through racism, hysteria and deliciousness all in the name of acquitting MSG in the court of public opinion.
 
Previous Episodes Mentioned:
<a href="https://podcasts.apple.com/au/podcast/the-wholesome-show/id1147011021?i=1000494928667">Musical Maladies - And Fakes!</a>
 
Sources
<ul>
<li>Jennifer LeMesurier’s Poroi (An Interdisciplinary Journal of Rhetorical Analysis and Invention) article: <a href="https://pubs.lib.uiowa.edu/poroi/article/3395/galley/112281/view/">Uptaking Race: Genre, MSG, and Chinese Dinner</a></li>
<li>Ian Mosby’s: <a href="https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.672.4477&amp;rep=rep1&amp;type=pdf">‘That Won-Ton Soup Headache’: The Chinese Restaurant Syndrome, MSG and the Making of American Food, 1968–1980</a></li>
<li>Michael Blanding’s article in Colgate Magazine: <a href="https://news.colgate.edu/magazine/2019/02/06/the-strange-case-of-dr-ho-man-kwok/">The Strange Case of Dr Ho Man Kwok</a></li>
<li>Richard D Lyons article in the New York Times: <a href="https://timesmachine.nytimes.com/timesmachine/1968/05/19/issue.html">‘Chinese Restaurant Syndrome’ Puzzles Doctors. May 19 1968</a></li>
<li>Herbert Schaumburg and Robert Byck’s article in Science: <a href="https://www.jstor.org/stable/1726504">Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome</a></li>
<li>This American Life’s <a href="https://www.thisamericanlife.org/668/transcript">The Long Fuse</a></li>
<li>The Washington Post’s: <a href="https://www.washingtonpost.com/archive/opinions/1981/03/29/beware-of-mushers-knee-and-hookers-elbow/e8fa0278-7a33-4068-830d-9c05b156d4b6/">Beware of musher's knee and hooker's elbow</a></li>
<li>Umami Information Center: <a href="https://www.umamiinfo.com/ikedakikunae/">Kikunae Ikeda</a></li>
</ul>

From tales of historical idiocracy and scientific genius to weird and wacky cultural phenomena, Dr Rod Lamberts and Dr Will Grant are here to take you on a wild conversational journey, deep diving into the crevices of science, history and culture that you never knew existed. 

From tales of historical idiocracy and scientific genius to weird and wacky cultural phenomena, Dr Rod Lamberts and Dr Will Grant are here to take you on a wild conversational journey, deep diving into the crevices of science, history and culture that you never knew existed.

Science stories for people who sit up the back of…

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