Dr. Victor Van Berkel lost his father to lung cancer — the deadliest cancer in the U.S., in part because it’s so difficult to detect early. That loss inspired Breath Diagnostics, a start-up using breath samples and microchip technology to identify cancer. But groundbreaking science doesn’t always translate into a sustainable business. After years of stalled leadership and mounting debt, investor Ivan Lo stepped in — buying the debt, restructuring the company and becoming CEO. When a Mayo Clinic partnership revealed they needed to fix some technical issues first, they hit pause to get it right — even if it meant going it alone for a while.

 

In this episode, Ben Walter and Kathleen Griffith speak with Victor and Ivan about making hard bets, the real costs and rewards of scientific startups and why leading with conviction sometimes matters more than consensus. These are The Unshakeables.

Dr. Victor Van Berkel lost his father to lung cancer &mdash; the deadliest cancer in the U.S., in part because it&rsquo;s so difficult to detect early. That loss inspired Breath Diagnostics, a start-up using breath samples and microchip technology to identify cancer. But groundbreaking science doesn&rsquo;t always translate into a sustainable business. After years of stalled leadership and mounting debt, investor Ivan Lo stepped in &mdash; buying the debt, restructuring the company and becoming CEO. When a Mayo Clinic partnership revealed they needed to fix some technical issues first, they hit pause to get it right &mdash; even if it meant going it alone for a while.
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In this episode, Ben Walter and Kathleen Griffith speak with Victor and Ivan about making hard bets, the real costs and rewards of scientific startups and why leading with conviction sometimes matters more than consensus. These are The Unshakeables.

The Unshakeables podcast dives into inspiring stories from real small business owners across America who power their communities every day. Join Ben Walter, CEO of Chase for Business, and co-host Kathleen Griffith as they hear from guests who share their make-or-break moments that changed everything. Produced in collaboration with iHeartMedia's Ruby Studio, The Unshakeables has won multiple awards, including Gold at the 2025 Signal Awards. The speakers’ opinions belong to them and may differ from opinions of J.P. Morgan Chase & Co. and its affiliates. Views presented on this podcast are those of the speakers; they are as of the podcast release date and they may not materialize. JPMorgan Chase Bank, N.A. Member FDIC. ©2026 JPMorgan Chase & Co.

The Unshakeables podcast dives into inspiring stories from real small business owners across America who power their communities every day. Join Ben Walter, CEO of Chase for Business, and co-host Kathleen Griffith as they hear from guests who share their make-or-break moments that changed everything. Produced in collaboration with iHeartMedia's Ruby Studio, The Unshakeables has won multiple awards, including Gold at the 2025 Signal Awards. The speakers&rsquo; opinions belong to them and may differ from opinions of J.P. Morgan Chase &amp; Co. and its affiliates. Views presented on this podcast are those of the speakers; they are as of the podcast release date and they may not materialize. JPMorgan Chase Bank, N.A. Member FDIC. &copy;2026 JPMorgan Chase &amp; Co.

The Unshakeables

The Business of Early Detection: Breath Diagnostics

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/c486b404-8ff2-46fe-b969-b3f70150c498/transcript