Israel has confirmed it caused an explosion at a refugee camp in the northern Gaza Strip, saying it targeted a Hamas leader.
Reuters reports Palestinian medics say at least 50 are dead.
CNN reports the Israel Defence Force says it was targeting a very senior Hamas commander in the area around the camp.
US Correspondent Richard Arnold told Mike Hosking that the director of a hospital nearby said that hundreds of dead and injured have arrived at the hospital, and many are still under the rubble.
This figure is still unconfirmed.
LISTEN ABOVE

Mike's Minute: It's still our year
01:44

Steve Price: Australian correspondent on One Nation looking to bring down the number of international students
07:12

Commentary Box: Andrew Saville and Jason Pine discuss the All Blacks' loss and the Warriors' upcoming clash against the Knights
11:27