Katalin Karikó is a Hungarian-American biochemist. She is one of the inventors of mRNA technology.

Full transcript available at: thejspod.com.

Episode recorded on 15 February 2023.

Katalin Karikó is a Hungarian-American biochemist. She is one of the inventors of mRNA technology.
Full transcript available at: thejspod.com.
Episode recorded on 15 February 2023.

Joe Walker hosts refreshingly in-depth conversations with founders, scientists, scholars, economists, and public intellectuals.

Joe Walker hosts refreshingly in-depth conversations with founders, scientists, scholars, economists, and public intellectuals.

The Joe Walker Podcast

Katalin Karikó — Forging the mRNA Revolution

In this special end-of-year episode, the tables are turned: I’m the guest, and I’m interviewed by Zac Gross — an Australian macroeconomist and long-time listener of the show.

We reflect on what I learned on the podcast in 2025 and what I changed my mind about. We also discuss the behind-the-scenes work of running the show, and my plans for 2026.

Sponsors
Vanta: helps businesses automate security and compliance needs. For a limited time, get one thousand dollars off Vanta at vanta.com/joe. Use the discount code "JOE".

To sponsor a future episode, go to https://josephnoelwalker.com/sponsor/

In this special end-of-year episode, the tables are turned: I&rsquo;m the guest, and I&rsquo;m interviewed by <a href="https://x.com/ZacGross">Zac Gross</a> &mdash; an Australian macroeconomist and long-time listener of the show.
We reflect on what I learned on the podcast in 2025 and what I changed my mind about. We also discuss the behind-the-scenes work of running the show, and my plans for 2026.
Sponsors
<ul>
<li>Vanta: helps businesses automate security and compliance needs. For a limited time, get one thousand dollars off Vanta at vanta.com/joe. Use the discount code "JOE".</li>
</ul>
To sponsor a future episode, go to https://josephnoelwalker.com/sponsor/

2025 Retrospective — A Listener (Zac Gross) Interviews Me

Glyn Davis and Terry Moran are two of the very small number of Australians who have literally sat in the Cabinet Room, week after week, watching the machinery of government operate from the inside.

Both served as Secretary of the Department of the Prime Minister and Cabinet (PM&C) — the most senior public servant in Australia. Terry held the role from 2008 to 2011 (including during the Global Financial Crisis). Glyn held it from 2022 to 2025.

Both have also held equivalent roles at the state level: Glyn as Director-General of the Office of the Cabinet in Queensland (1995–96), and Terry as Secretary of the Victorian Department of Premier and Cabinet (2000–08). Before PM&C, Glyn was Vice-Chancellor of the University of Melbourne for thirteen years, and later ran the Paul Ramsay Foundation (Australia’s largest philanthropic foundation). Terry’s career spanned senior roles across the Commonwealth and Victorian public services, including as CEO of Victoria’s Office of the State Training Board, inaugural CEO of the Australian National Training Authority, and Queensland’s Director-General of Education. He later served as Chancellor of Federation University.

In this episode, we trace the routines, conventions, and systems that shape power in Canberra. Where, exactly, does a prime minister’s power come from? What separates a good Cabinet submission from a bad one? What actually happens in the Cabinet room once the doors close? How does Australia’s Westminster model differ from the UK and Canada? And why is Australia so unusually good at bureaucracy?

(Episode recorded on 8 December 2025.)

Sponsors
Vanta: helps businesses automate security and compliance needs. For a limited time, get one thousand dollars off Vanta at vanta.com/joe. Use the discount code "JOE".

To sponsor a future episode, go to https://josephnoelwalker.com/sponsor/

Glyn Davis and Terry Moran are two of the very small number of Australians who have literally sat in the Cabinet Room, week after week, watching the machinery of government operate from the inside.
Both served as Secretary of the Department of the Prime Minister and Cabinet (PM&amp;C) &mdash; the most senior public servant in Australia. Terry held the role from 2008 to 2011 (including during the Global Financial Crisis). Glyn held it from 2022 to 2025.
Both have also held equivalent roles at the state level: Glyn as Director-General of the Office of the Cabinet in Queensland (1995&ndash;96), and Terry as Secretary of the Victorian Department of Premier and Cabinet (2000&ndash;08). Before PM&amp;C, Glyn was Vice-Chancellor of the University of Melbourne for thirteen years, and later ran the Paul Ramsay Foundation (Australia&rsquo;s largest philanthropic foundation). Terry&rsquo;s career spanned senior roles across the Commonwealth and Victorian public services, including as CEO of Victoria&rsquo;s Office of the State Training Board, inaugural CEO of the Australian National Training Authority, and Queensland&rsquo;s Director-General of Education. He later served as Chancellor of Federation University.
In this episode, we trace the routines, conventions, and systems that shape power in Canberra. Where, exactly, does a prime minister&rsquo;s power come from? What separates a good Cabinet submission from a bad one? What actually happens in the Cabinet room once the doors close? How does Australia&rsquo;s Westminster model differ from the UK and Canada? And why is Australia so unusually good at bureaucracy?
(Episode recorded on 8 December 2025.)
Sponsors
<ul>
<li>Vanta: helps businesses automate security and compliance needs. For a limited time, get one thousand dollars off Vanta at vanta.com/joe. Use the discount code "JOE".</li>
</ul>
To sponsor a future episode, go to https://josephnoelwalker.com/sponsor/

Cabinet is Australia's Operating System — Here's How It Works (Glyn Davis & Terry Moran)

2,500 years of strategic history, 11 books, one afternoon. 

Hugh White is Australia's foremost strategic thinker: former senior adviser to Defence Minister Kim Beazley and Prime Minister Bob Hawke, Deputy Secretary for Strategy and Intelligence in Defence, inaugural Director of ASPI, and principal author of the 2000 Defence White Paper. He is now Emeritus Professor of Strategic Studies at the Australian National University.

Before this conversation, I asked Hugh for the eleven books that most shaped his thinking on strategy, international relations and defence policy. We work through them one by one — what each book argues, what it gets right and wrong, how it shaped his worldview — and use them to tackle the big questions: why great powers start disastrous wars, how international orders collapse, and how Australia and America should respond to the rise of China.

Episode resources
Hugh's strategy reading list: https://josephnoelwalker.com/hugh-whites-strategy-reading-list/
Hugh's 1993 Tathra note: https://josephnoelwalker.com/hugh-whites-tathra-note/

Sponsors
Eucalyptus: the Aussie startup providing digital healthcare clinics to help patients around the world take control of their quality of life. Euc is looking to hire ambitious young Aussies and Brits. You can check out their open roles at eucalyptus.health/careers.
Vanta: helps businesses automate security and compliance needs. For a limited time, get one thousand dollars off Vanta at vanta.com/joe. Use the discount code "JOE".

To sponsor a future episode, go to https://josephnoelwalker.com/sponsor/

2,500 years of strategic history, 11 books, one afternoon.&nbsp;
Hugh White is Australia's foremost strategic thinker: former senior adviser to Defence Minister Kim Beazley and Prime Minister Bob Hawke, Deputy Secretary for Strategy and Intelligence in Defence, inaugural Director of ASPI, and principal author of the 2000 Defence White Paper. He is now Emeritus Professor of Strategic Studies at the Australian National University.
Before this conversation, I asked Hugh for the eleven books that most shaped his thinking on strategy, international relations and defence policy. We work through them one by one &mdash; what each book argues, what it gets right and wrong, how it shaped his worldview &mdash; and use them to tackle the big questions: why great powers start disastrous wars, how international orders collapse, and how Australia and America should respond to the rise of China.
Episode resources
<ul>
<li>Hugh's strategy reading list: https://josephnoelwalker.com/hugh-whites-strategy-reading-list/</li>
<li>Hugh's 1993 Tathra note: https://josephnoelwalker.com/hugh-whites-tathra-note/</li>
</ul>
Sponsors
<ul>
<li>Eucalyptus: the Aussie startup providing digital healthcare clinics to help patients around the world take control of their quality of life. Euc is looking to hire ambitious young Aussies and Brits. You can check out their open roles at eucalyptus.health/careers.</li>
<li>Vanta: helps businesses automate security and compliance needs. For a limited time, get one thousand dollars off Vanta at vanta.com/joe. Use the discount code "JOE".</li>
</ul>
To sponsor a future episode, go to https://josephnoelwalker.com/sponsor/

Katalin Karikó — Forging the mRNA Revolution

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