In this episode, Geneticist Prof Jenny Graves joins host Dr David Lim to discuss the strange biology of the Y chromosome, its surprising links with men’s health, and why some men are more vulnerable to losing it as they age:
Why the loss of the Y chromosome (LOY) is more common than other chromosomal changes 
Links to cardiac fibrosis, kidney disease, bladder cancer, Alzheimer’s disease, cancers, and immune dysregulation 
How mosaicism for the Y chromosome develops with age 
How future screening for LOY help risk stratify patients, sharpen lifestyle counselling, and monitor more closely for conditions  
A long-view perspective on the evolution and future of the human Y chromosome

Host: Dr David Lim | Total Time: 34 mins

Expert: Prof Jenny Graves, Geneticist

In this episode, Geneticist Prof Jenny Graves joins host Dr David Lim to discuss the strange biology of the Y chromosome, its surprising links with men&rsquo;s health, and why some men are more vulnerable to losing it as they age:
<ul>
<li>Why&nbsp;the&nbsp;loss of the Y chromosome&nbsp;(LOY)&nbsp;is more common than other chromosomal changes&nbsp;</li>
<li>Links to&nbsp;cardiac fibrosis, kidney disease, bladder cancer, Alzheimer&rsquo;s disease, cancers, and immune dysregulation&nbsp;</li>
<li>How mosaicism for the Y chromosome develops with age&nbsp;</li>
<li>How future screening for LOY&nbsp;help risk stratify patients, sharpen lifestyle counselling, and&nbsp;monitor&nbsp;more closely for conditions&nbsp;&nbsp;</li>
<li>A long-view perspective on the evolution and future of the human Y chromosome</li>
</ul>
Host: Dr David Lim | Total Time: 34 mins
Expert: Prof Jenny Graves, Geneticist

The Clinical Takeaway podcast for healthcare professionals features leading experts on important topics that can positively change the way you practice. Each episode is eligible for continued professional development (CPD).