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Pauline Gross was a seamstress in 1895 who had seen family members die at an early age from cancer. At the time, one of her clients was a pathologist by the name of Dr Aldred Scott Warthin and confided in him her fear that that this would be her fate too. The two combined to record the most comprehensive family history ever created. Dr Warthin called them ‘Family G’.

In the 1960s, Dr Henry T Lynch who revived the search for the members of Family G. Through family gatherings and meetings, he managed to track down over 650 family members, of which, 95 had a history of cancer. He noted that they had an Autosomal Dominant disorder that increased their incidence of uterine and gastrointestinal cancers. Dr Lynch called it a ‘Cancer Family Syndrome’. Today, it is known as Lynch syndrome.

Our special guests include:
Ami McKay: an award winning novelist who has written ‘Daughter of Family G/Before my time: a memoir of love & fate’. Ami has also produced the radio documentary ‘Daughter of Family G’ available at amimckay.com
Dr Tristan Rutland: Anatomical pathologists at Liverpool hospital and based at Western Sydney University with a PhD in colorectcal cancer. Dr Rutland was the recipient of the Konrad Muller RCPA Outstanding Teaching Award


Professor Graeme Suthers: National Director of Genetics for Sonic Pathology Australia who trained in clinical and laboratory genetics in Sydney, Adelaide, and Oxford.

This is the story of Lynch syndrome.

Pauline Gross was a seamstress in 1895 who had seen family members die at an early age from cancer. At the time, one of her clients was a pathologist by the name of Dr Aldred Scott Warthin and confided in him her fear that that this would be her fate too. The two combined to record the most comprehensive family history ever created. Dr Warthin called them &lsquo;Family G&rsquo;.
In the 1960s, Dr Henry T Lynch who revived the search for the members of Family G. Through family gatherings and meetings, he managed to track down over 650 family members, of which, 95 had a history of cancer. He noted that they had an Autosomal Dominant disorder that increased their incidence of uterine and gastrointestinal cancers. Dr Lynch called it a &lsquo;Cancer Family Syndrome&rsquo;. Today, it is known as Lynch syndrome.
Our special guests include:
<ul>
<li>Ami McKay: an award winning novelist who has written &lsquo;Daughter of Family G/Before my time: a memoir of love &amp; fate&rsquo;. Ami has also produced the radio documentary &lsquo;Daughter of Family G&rsquo; available at <a href="https://amimckay.com/">amimckay.com</a></li>
<li>Dr Tristan Rutland: Anatomical pathologists at Liverpool hospital and based at Western Sydney University with a PhD in colorectcal cancer. Dr Rutland was the recipient of the Konrad Muller RCPA Outstanding Teaching Award </li>
<li>Professor Graeme Suthers: National Director of Genetics for Sonic Pathology Australia who trained in clinical and laboratory genetics in Sydney, Adelaide, and Oxford.</li>
</ul>
This is the story of Lynch syndrome.

A weekly podcast recorded in Adelaide that puts South Australian passion on centre stage with a featured guest who joins us each week as a co-presenter to share how they're pursuing their passions. We venture across topics as diverse as history, wine, food, art, music, relationships, critical thinking, health, news, interviews, chat and quizzes. 

Every single interview, every single show, unlocks insights into what drives people to be doing what they're doing and what keeps them striving. 

The Adelaide Show is produced by Steve Davis and Nigel Dobson-Keeffe.

Please subscribe to our In Crowd list; you get an email each Friday (when we have published a new episode) with an overview of that week's show. Plus, consider joining our Inner Circle; a small group of passionate South Aussies who allow us to pick their brains and gain interviewee suggestions.

This podcast began life as Another Boring Thursday Night In Adelaide from episodes 1-79.

A podcast recorded in Adelaide that puts South Australian passion on centre stage with a featured guest who joins us each week as a co-presenter to share how they're pursuing their passions. We venture across topics as diverse as history, wine, ...

The Adelaide Show

A podcast recorded in Adelaide that puts South Australian passion on centre stage with a featured guest who joins us to share how they're pursuing their passions. We venture across topics as diverse as history, wine, food, art, music, relationships, critical thinking, health, and general news. Every single interview, every single show, unlocks insights into what drives people to be doing what they're doing and what keeps them striving. The Adelaide Show is produced by Steve Davis, and ends with an original song by a South Australian artist. Please subscribe to our In Crowd list; you get an email each Friday with an overview of that week's show. This podcast began life as Another Boring Thursday Night In Adelaide from episodes 1-79.

A podcast recorded in Adelaide that puts South Australian passion on centre stage with a featured guest who joins us to share how they're pursuing their passions. We venture across topics as diverse as history, wine, food, art, music, relationships, critical thinking, health, and general news. Every single interview, every single show, unlocks insights into what drives people to be doing what they're doing and what keeps them striving. The Adelaide Show is produced by Steve Davis, and ends with an original song by a South Australian artist. Please subscribe to our In Crowd list; you get an email each Friday with an overview of that week's show. This podcast began life as Another Boring Thursday Night In Adelaide from episodes 1-79.

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