Game week is here. John Harris opens the Wednesday edition of Texans All-Access from the Texans Radio Studio with the Texans four days out from hosting the Buffalo Bills at Reliant Stadium in the 2026 regular season opener.

Executive Vice President and General Manager Nick Caserio joins Marc Vandermeer and John Harris in studio for his weekly visit, covering the state of the program coming out of training camp, how this roster differs from the three that came before it, the reshaped offensive line, T Blake Fisher's jump in year three, WR Kayshon Boutte's arrival, RB Woody Marks' second-year leap, and a tight end room he calls deep and complementary. Caserio also runs through his Week 1 scouting report on Buffalo — Brandon Beane's roster building, the transition from Sean McDermott to Joe Brady, Jim Leonhard's new defensive scheme, and the challenge of preparing for QB Josh Allen. He closes with thoughts on artificial intelligence in football operations, the evolving kicking-game rules, P Kai Kroeger winning the punting job, and the Rivalries uniforms.

Then it's Men Behind the Mics. Marc Vandermeer sits down with Chris Brown, the play-by-play voice of the Buffalo Bills, for the view from the other sideline: what DJ Moore has meant to the Bills' passing game, the new three-four front under Leonhard, how Joe Brady's leadership is landing in the locker room, the AFC East and AFC contender picture, and what Buffalo has to do to move the ball on a Texans defense Brown says will eat one-dimensional offenses alive.

John Harris then walks through the first injury report of the season — a notably clean one for Houston — before rookie LB Aiden Fisher closes the show. The Indiana product and national champion talks about the grind of a rookie year, learning from LB Azeez Al-Shaair and LB Henry To'oTo'o, wearing the green dot, playing for special teams coordinator Frank Ross, and swinging from preparing for a national championship game to preparing for Josh Allen.

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EVP/GM Nick Caserio Talks Bills Matchup | Texans All-Access

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