The pellagra epidemic of the early 20th century may have been the deadliest epidemic of a specific nutrient deficiency in U.S. history. Part one covers what it is, its appearance in 19th-century Italy, and the first reports of it in the U.S.
Research:

Behind the Scenes Minis: Paddles and The British Museum
31:02

Ashurbanipal
37:29

Six Impossible Episodes: Back-to-Court
41:15