This episode goes out to all the haters who said StraightioLab was "too structured" and "made too much sense." In it, George and Sam welcome comedian Ike Ufomadu who is also the first str*ight m*le guest and they talk about everything from Regis Philbin to The Weakest Link to the mysterious disappearances happening around Ike's ominous foundation. Reality is blurred, friendships are tested, and it even ends on a cliffhanger, which is a StraightioLab first.