Today's biggest winners and losers in the stock market.

On this episode of Stock Movers:

- Nike (NKE) shares slide as much as 14%, to the lowest level since Feb. 2015, after the sportswear company forecast a revenue drop of as much as 4% for the fourth quarter, and warned sales declines could persist for the rest of this calendar year.
- Intel (INTC) shares are up 9.8% on Wednesday, after the chipmaker agreed to pay $14.2 billion to buy back half of a plant in Ireland. D.A. Davidson wrote that the move bodes well for the company’s turnaround story.

- Shares of Eli Lilly (LLY) jump as much as 4.5% after the FDA approved the drugmaker’s obesity pill, Foundayo, under the agency’s National Priority Voucher pilot program. US-traded shares of rival Novo Nordisk fell as much as 2.6% after the approval