Today's biggest winners and losers in the stock market.

On this episode of Stock Movers:

• Galderma shares slumped the most in more than a year after the US Food and Drug Administration turned down the Swiss dermatology firm’s rival Botox treatment Relfydess.
• Associated British Foods reported lower sales at its Primark budget fashion chain and a profit-hit at its sugar unit due to the war in Iran, as the conglomerate prepares to separate its clothing and food divisions.
• CMC Markets shares soared 22% to a fresh record after the UK financial derivatives dealer raised its guidance for 2027 net operating income citing strong momentum.