From starring in hilarious comedy sketches at the Second City and Mr. Show to a prolific cartoon voice-over career, Jill Talley is inspiring the next generation of future comedy greats like herself. In this episode, Jill reflects on the evolution of Karen’s character, ad-libbing with Mr. Lawrence in the studio, her thoughts on the famous Mrs. Puff conspiracy theories, and what it’s like to voice Squidina Star on The Patrick Star Show.