Because the vast majority of longevity research is based on white people, Mangesh asks the question, what about HIS body? He talks with a Yale researcher from Delhi who explains how centuries of colonialism have shaped South Asian epigenetics, leading to stark inequalities—and more big questions. And then, Mangesh heads to India, where he subjects himself to high-tech services at a biohacking lab and visits a traditional ayurvedic clinic. Back home in New York, his mom reflects on life after loss, and how much longer she really wants to live. Plus: Mangesh’s teenage son explains looksmaxxing and rates his dad’s face.
Learn more about Raghav Sehgal’slongevity research
Check out Reverse Infinity and Shree Shanti Wellness in Goa
Try a recipe for pani puri 
Listen to the BBC audio documentary 3 Million, about the Bengal famine

Special thanks to Azadi Records and Bliss Samsa for their beautiful tracks, and Botany for the score. 

Episode collage art by Vahini Shori.

Because the vast majority of longevity research is based on white people, Mangesh asks the question, what about HIS body? He talks with a Yale researcher from Delhi who explains how centuries of colonialism have shaped South Asian epigenetics, leading to stark inequalities&mdash;and more big questions. And then, Mangesh heads to India, where he subjects himself to high-tech services at a biohacking lab and visits a traditional ayurvedic clinic. Back home in New York, his mom reflects on life after loss, and how much longer she really wants to live. Plus: Mangesh&rsquo;s teenage son explains looksmaxxing and rates his dad&rsquo;s face.
<ul>
<li aria-level="1">Learn more about <a href="https://www.raghav-sehgal.com/">Raghav Sehgal&rsquo;s</a> <a href="https://www.nature.com/articles/s43587-025-00958-3">longevity research</a></li>
<li aria-level="1">Check out <a href="https://www.reverseinfinity.com/">Reverse Infinity</a> and <a href="https://www.sreeshantiayurveda.com/">Shree Shanti Wellness</a> in Goa</li>
<li aria-level="1">Try a <a href="https://www.seriouseats.com/pani-puri-recipe-11693199">recipe for pani puri</a>&nbsp;</li>
<li aria-level="1">Listen to the <a href="https://www.bbc.com/audio/brand/m001wr57">BBC audio documentary 3 Million</a>, about the Bengal famine</li>
</ul>
Special thanks to <a href="https://azadirecords.com/">Azadi Records</a> and <a href="https://linktr.ee/blisssamsa">Bliss Samsa</a> for their beautiful tracks, and <a href="https://botany.bandcamp.com/music">Botany</a> for the score.&nbsp;
Episode collage art by <a href="https://www.vahinishori.com/">Vahini Shori</a>.

Mangesh Hattikudur (Part-Time Genius, Mental_Floss) dives into the booming business of living forever—meeting the scientists, biopunks, and entrepreneurs trying to turn immortality into reality, and framing death as a choice. But the more he learns about an immortal future, the more he finds himself drawn to the people he loves…and wondering if an endless life can be a meaningful one.

Skyline Drive: How to Live Forever is the follow up to the beloved Skyline Drive (season 1), named a “Series Essential” — an Apple Podcasts honor for top-tier narrative podcasts — and highlighted on several Best of Year lists including NYMag, Guardian, and others. 

Mangesh Hattikudur (Part-Time Genius, Mental_Floss) dives into the booming business of living forever&mdash;meeting the scientists, biopunks, and entrepreneurs trying to turn immortality into reality, and framing death as a choice. But the more he learns about an immortal future, the more he finds himself drawn to the people he loves&hellip;and wondering if an endless life can be a meaningful one.
Skyline Drive: How to Live Forever is the follow up to the beloved Skyline Drive (season 1), named a &ldquo;Series Essential&rdquo; &mdash; an Apple Podcasts honor for top-tier narrative podcasts &mdash; and highlighted on several Best of Year lists including NYMag, Guardian, and others.&nbsp;

Skyline Drive: How to Live Forever

Skyline Drive has been selected as an Apple Podcasts Series Essential! Listen ad-free for a limited time.

When Mangesh Hattikudur (Part-Time Genius, Humans Growing Stuff) set out to do a big, sweeping show on astrology, he didn’t realize the first interview would change the course of his life. But as he tries to put his world back together, he realizes the incredible ways astrology presents itself in modern society: from NASA employees who keep their belief in astrology in the closet, to world leaders who’ve used astrologers to guide foreign policy, to moneyball statisticians who use astrology more than statistics to build baseball teams, to a little shop in India where your fortune was written for you centuries ago, and is waiting for you to come claim it. Over the course of 8 episodes, Mangesh tries to decipher why we keep looking to the stars for answers, and what happens when you don’t believe in astrology, but astrology keeps happening to you.

Skyline Drive has been selected as an Apple Podcasts Series Essential! Listen ad-free for a limited time.
When Mangesh Hattikudur (Part-Time Genius, Humans Growing Stuff) set out to do a big, sweeping show on astrology, he didn&rsquo;t realize the first interview would change the course of his life. But as he tries to put his world back together, he realizes the incredible ways astrology presents itself in modern society: from NASA employees who keep their belief in astrology in the closet, to world leaders who&rsquo;ve used astrologers to guide foreign policy, to moneyball statisticians who use astrology more than statistics to build baseball teams, to a little shop in India where your fortune was written for you centuries ago, and is waiting for you to come claim it. Over the course of 8 episodes, Mangesh tries to decipher why we keep looking to the stars for answers, and what happens when you don&rsquo;t believe in astrology, but astrology keeps happening to you.

Skyline Drive

Untapped Potential

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/7b19a181-fd3a-4135-91f1-b48d010aae70/transcript