The Global Organized Crime Index 2023 reveals the continuing rise of organized crime globally, with 83% of the world’s population living in conditions of high criminality. Conversely, the number of people living in conditions of low resilience to organized crime globally has declined significantly: now, 62% of the world’s population, compared to 79.4% in 2021. Still, while more people today live in countries characterized as having high resilience, when comparing global resilience to the rise in the pervasiveness of criminality, the data shows that response frameworks have failed to meet the organized crime threat. The widening gap between organized crime and our collective resilience efforts highlights the urgent need for informed, practical strategies to combat organized crime globally. Dr Mbuyiseni Ndlozi was joined by Mark Shaw, director at the Global Initiative for Transnational Organized Crime and, Chad Thomas who is an organized crime investigator, IRS Forensic Investigations.