For many women, the real challenge isn’t just unexplained health problems, it’s being heard when they seek help.

Jay sits down with Dr. Thaïs Aliabadi, or "Dr. A", to unpack a silent crisis affecting millions of women around the world: undiagnosed PCOS and endometriosis. This isn’t just a discussion about fertility, but a masterclass on hormones, inflammation, mental health, and the painful reality of medical gaslighting. PCOS, a condition shaped by insulin resistance, hormonal imbalance, chronic inflammation, and neurological disruption, is often overlooked, leaving women struggling with anxiety, depression, weight gain, irregular periods, and infertility without answers. Dr. A shares how insulin resistance acts as the “first domino,” triggering a domino effect that impacts everything from ovulation to mood, and emphasizes that true healing requires addressing all four pillars, not just masking symptoms with birth control.

Dr. A challenges the outdated belief that painful periods are “normal,” explaining that severe pain, painful sex, chronic bloating, bladder symptoms, and bowel discomfort are signs something deeper may be wrong. She reveals that diagnosis takes an average of 9–11 years, and that many women are told their pain is psychological before they’re ever taken seriously.

Through both science and lived clinical experience, she makes it clear: when inflammation and hormones are out of balance, mental health suffers too. Anxiety, depression, brain fog, and eating disorders are not personal failings, they are often physiological signals that something deeper is happening in the body.

In this interview, you'll learn:

How to Recognize the Signs of PCOS Early

How to Reduce Insulin Resistance Naturally

How to Tell if Your Period Pain Is “Normal”

How to Protect Your Fertility in Your 20s and 30s

How to Balance Hormones Beyond Birth Control

How to Spot Hidden Symptoms of Endometriosis

How to Lower Inflammation Through Lifestyle Changes

If there’s one thing to take away from this conversation, it’s this: your body is not working against you, it’s communicating with you. Pain is not weakness. It is a signal and you deserve to have those signals taken seriously.

To learn more about Dr. A’s advocacy on women’s health, check out: https://www.shemdpodcast.com/ 

With Love and Gratitude,

Jay Shetty

JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe here: https://news.jayshetty.me/subscribe  

Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast 

What We Discuss:

00:00 Intro

02:58 Are We Facing a Fertility Crisis?

03:58 What Is PCOS?

07:13 Why PCOS Often Goes Undiagnosed

09:15 The Impact of Insulin Resistance

15:06 Making PCOS Patients Insulin-Sensitive

19:37 The Nutritional Effects of GLP-1 Medications

22:14 High Androgens and Chronic Inflammation

25:39 How Hormonal Imbalances Affect the Brain

29:25 Why Birth Control Alone Isn’t Enough

31:23 How to Know If You Have PCOS

35:01 Painful Periods Are Not Normal

36:47 What Is Endometriosis?

46:07 The Most Effective Treatment Approach for Endometriosis

49:20 The Risks of Ignoring Endometriosis

53:09 How to Use Birth Control Strategically

56:04 What to Do If Egg Freezing Isn’t an Option

57:53 The Link Between Endometriosis and Leaky Gut

01:00:33 Potential IVF Complications Explained

01:04:38 A Scientific Approach to Infertility

01:10:01 What to Do If You’re Not Getting Pregnant

Episode Resources:

Website: https://ovii.com/ 

Website: https://www.draliabadi.com/ 

YouTube: https://www.youtube.com/channel/UCrej0PO97bg8GRMogtcKbbA 

Facebook: https://www.facebook.com/ThaisAliabadiMd 

Instagram: https://www.instagram.com/drthaisaliabadi/ 

For many women, the real challenge isn&rsquo;t just unexplained health problems, it&rsquo;s being heard when they seek help.
Jay sits down with Dr. Tha&iuml;s Aliabadi, or "Dr. A", to unpack a silent crisis affecting millions of women around the world: undiagnosed PCOS and endometriosis. This isn&rsquo;t just a discussion about fertility, but a masterclass on hormones, inflammation, mental health, and the painful reality of medical gaslighting. PCOS, a condition shaped by insulin resistance, hormonal imbalance, chronic inflammation, and neurological disruption, is often overlooked, leaving women struggling with anxiety, depression, weight gain, irregular periods, and infertility without answers. Dr. A shares how insulin resistance acts as the &ldquo;first domino,&rdquo; triggering a domino effect that impacts everything from ovulation to mood, and emphasizes that true healing requires addressing all four pillars, not just masking symptoms with birth control.
Dr. A challenges the outdated belief that painful periods are &ldquo;normal,&rdquo; explaining that severe pain, painful sex, chronic bloating, bladder symptoms, and bowel discomfort are signs something deeper may be wrong. She reveals that diagnosis takes an average of 9&ndash;11 years, and that many women are told their pain is psychological before they&rsquo;re ever taken seriously.
Through both science and lived clinical experience, she makes it clear: when inflammation and hormones are out of balance, mental health suffers too. Anxiety, depression, brain fog, and eating disorders are not personal failings, they are often physiological signals that something deeper is happening in the body.
In this interview, you'll learn:
How to Recognize the Signs of PCOS Early
How to Reduce Insulin Resistance Naturally
How to Tell if Your Period Pain Is &ldquo;Normal&rdquo;
How to Protect Your Fertility in Your 20s and 30s
How to Balance Hormones Beyond Birth Control
How to Spot Hidden Symptoms of Endometriosis
How to Lower Inflammation Through Lifestyle Changes
If there&rsquo;s one thing to take away from this conversation, it&rsquo;s this: your body is not working against you, it&rsquo;s communicating with you. Pain is not weakness. It is a signal and you deserve to have those signals taken seriously.
To learn more about Dr. A&rsquo;s advocacy on women&rsquo;s health, check out: <a href="https://www.shemdpodcast.com/">https://www.shemdpodcast.com/</a>&nbsp;
With Love and Gratitude,
Jay Shetty
JAY&rsquo;S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX
Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe here: <a href="https://news.jayshetty.me/subscribe">https://news.jayshetty.me/subscribe</a> &nbsp;
Check out our Apple subscription to unlock bonus content of On Purpose! <a href="https://lnk.to/JayShettyPodcast">https://lnk.to/JayShettyPodcast</a>&nbsp;
What We Discuss:
00:00 Intro
02:58 Are We Facing a Fertility Crisis?
03:58 What Is PCOS?
07:13 Why PCOS Often Goes Undiagnosed
09:15 The Impact of Insulin Resistance
15:06 Making PCOS Patients Insulin-Sensitive
19:37 The Nutritional Effects of GLP-1 Medications
22:14 High Androgens and Chronic Inflammation
25:39 How Hormonal Imbalances Affect the Brain
29:25 Why Birth Control Alone Isn&rsquo;t Enough
31:23 How to Know If You Have PCOS
35:01 Painful Periods Are Not Normal
36:47 What Is Endometriosis?
46:07 The Most Effective Treatment Approach for Endometriosis
49:20 The Risks of Ignoring Endometriosis
53:09 How to Use Birth Control Strategically
56:04 What to Do If Egg Freezing Isn&rsquo;t an Option
57:53 The Link Between Endometriosis and Leaky Gut
01:00:33 Potential IVF Complications Explained
01:04:38 A Scientific Approach to Infertility
01:10:01 What to Do If You&rsquo;re Not Getting Pregnant
Episode Resources:
Website: <a href="https://ovii.com/">https://ovii.com/</a>&nbsp;
Website: <a href="https://www.draliabadi.com/">https://www.draliabadi.com/</a>&nbsp;
YouTube: <a href="https://www.youtube.com/channel/UCrej0PO97bg8GRMogtcKbbA">https://www.youtube.com/channel/UCrej0PO97bg8GRMogtcKbbA</a>&nbsp;
Facebook: <a href="https://www.facebook.com/ThaisAliabadiMd">https://www.facebook.com/ThaisAliabadiMd</a>&nbsp;
Instagram: <a href="https://www.instagram.com/drthaisaliabadi/">https://www.instagram.com/drthaisaliabadi/</a>&nbsp;

I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace.

I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!

I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace.
I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!

On Purpose with Jay Shetty

My name is Jay Shetty, and my purpose is to make wisdom go viral. I’m fortunate to have fascinating conversations with the most insightful people in the world, and on my podcast, I’m sharing those conversations with you. New episodes Mondays and Fridays. Please rate and review the podcast if you enjoy it. Live life today ON PURPOSE.

My name is Jay Shetty, and my purpose is to make wisdom go viral. I’m fortunate to have fascinating conversations with the most insightful people in the world, and on my podcast, I’m sharing those conversations with you. New episodes Mondays and Fridays. Please rate and review the podcast if you enjoy it. Live life today ON PURPOSE.

WORLD’S TOP OBGYN Dr. Aliabadi: The #1 Hormone Problem Affecting Millions of Women (And The 4 Changes That Can Reverse It)

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/82b91d73-4169-486c-a007-b40a0064d371/transcript