Isaac Gampu is a South African comedian and actor best known for his starring role as Mkhandazonke on the SABC1 sitcom Him, Her and the Guys.
The son of actor Ken Gampu, he is also known for being part of the Blacks Only comedy circuit.
His break into comedy prominence came about when he won a Y-FM comedy contest in 2010.
Gampu has also performed in numerous other comedy venues and circuits including The Vernac Show, Waarheid Comedy Show, Hallelujah Comedy, Emalahleni Comedy Nite, 99% Zulu Comedy, You Only Laugh Once, 99% Xhosa Comedy, Giants of Comedy, The Annual Newcastle Comedy Festival and Comedy Under the Sun.