In this episode of Look Again: Mental Illness Re-examined, host Faydra Aldridge dives into the complex world of treatment-resistant schizophrenia—a condition where standard antipsychotic medications fail to alleviate symptoms like delusions and hallucinations. Joined by psychiatrist Dr. Diane McIntosh, they discuss why over 30% of those diagnosed with schizophrenia don't respond to typical treatments and explore alternative options available. From long-acting injectables to combinations of medications to ECT, Dr. McIntosh offers insights into promising strategies for people living with treatment resistant schizophrenia and the importance of comprehensive care, including social support. Learn more about current research, the challenges, and the hope for better treatment options for those living with this difficult condition.