What is ‘structure-based’ vaccine design? Before scientists used these techniques to design vaccines against Covid, they were testing them in the lab to combat RSV. Keren Landman joins the show to talk about how this respiratory virus endangers the lives of babies and the elderly. Then, we hear about an early RSV vaccine trial that cast a shadow over modern research, and how scientists, including our guests Jason McLellan and Barney Graham, later figured out how to create and stabilize a viral antigen’s spike protein to fight RSV.

What is ‘structure-based’ vaccine design? Before scientists used these techniques to design vaccines against Covid, they were testing them in the lab to combat RSV. Keren Landman joins the show to talk about how this respiratory virus endangers the lives of babies and the elderly. Then, we hear about an early RSV vaccine trial that cast a shadow over modern research, and how scientists, including our guests Jason McLellan and Barney Graham, later figured out how to create and stabilize a viral antigen’s spike protein to fight RSV.

Incubation is a new podcast that traces the history of humanity through viruses. We’ve all seen how the SARS CoV2 pandemic changed just about everything — from family life to work to politics –– but that’s just the latest installment in a long line of virus shake-ups. Other viruses –– influenza, HPV, smallpox, RSV –– have dramatically changed or endangered life as we know it. In many cases, scientists have been able to change the odds in favor of humanity. But deadly viruses persist — and containing them remains a scientific and technological challenge that each successive generation must take on.

Author and What’s Your Problem host Jacob Goldstein takes us on a journey with leading medical researchers, doctors and historians to trace key moments in our battles with viruses, breakthroughs in vaccine research, and the impact of vaccination campaigns.  These stories will help us better understand the evolutionary contest between humans and viruses, and how vaccines and new technologies are changing the score. Incubation drops weekly on Thursdays starting September 7.

Incubation is a new podcast that traces the history of humanity through viruses. We’ve all seen how the SARS CoV2 pandemic changed just about everything — from family life to work to politics –– but that’s just the latest installment in a long line of virus shake-ups. Other viruses –– influenza, HPV, smallpox, RSV –– have dramatically changed or endangered life as we know it. In many cases, scientists have been able to change the odds in favor of humanity. But deadly viruses persist — and containing them remains a scientific and technological challenge that each successive generation must take on.
Author and What’s Your Problem host Jacob Goldstein takes us on a journey with leading medical researchers, doctors and historians to trace key moments in our battles with viruses, breakthroughs in vaccine research, and the impact of vaccination campaigns.  These stories will help us better understand the evolutionary contest between humans and viruses, and how vaccines and new technologies are changing the score. Incubation drops weekly on Thursdays starting September 7.

Incubation

RSV: The Quest for a New Vaccine

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/4ecd5e24-2eb5-4781-987e-b06e012be2da/transcript

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