In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance.

We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins.

Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance.

Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Joovv: https://joovv.com/huberman

BetterHelp: https://betterhelp.com/huberman

Function: https://functionhealth.com/huberman

Eight Sleep: https://eightsleep.com/hubermanTimestamps

00:00:00 Dr. Craig Koniver

00:04:52 Sponsors: Joovv & BetterHelp

00:07:40 What is a Peptide?

00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health

00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation

00:18:43 BPC-157, Inflammation

00:23:27 BPC-157, Injection & Oral Forms; Injury Repair

00:28:43 Sourcing, Anabolic Steroids, Testosterone

00:34:48 Black & Gray Market, Compounding Pharmacies, Purity

00:38:20 Sponsor: AG1

00:39:51 Partnering with a Physician, LPS

00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects & Doses

00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep & Growth Hormone

00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides

00:58:45 Sponsor: Function & Eight Sleep

01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health

01:05:16 Prescriptions, Physicians & Trust

01:14:09 Agency in Your Health

01:17:13 MK-677, Appetite

01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing

01:21:10 Methylated B Vitamins, Homocysteine

01:24:47 Peptides for Sleep, Pinealon, Epitalon

01:31:03 Glycine, Liver Detoxification; Dosage

01:37:19 GLP-1, Compounding Pharmacies

01:39:03 Stem Cell Therapy, PRP

01:41:18 Thymosin Alpha-1, Cerebrolysin & Brain Health

01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses

01:50:20 Covid, NAD Infusion, NMN & NR Supplements

01:57:13 Nutritional Deficiencies; NAD Dose & Regimen, NMN & NR

02:07:53 PT-141, Vyleesi, Libido; Nausea

02:10:57 FDA Approval & Removal, Pharmaceutical Companies

02:20:17 Positivity, Mindset & Health

02:26:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures

In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance.We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins.Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance.Access the full show notes for this episode at <a href="https://www.hubermanlab.com/episode/dr-craig-koniver-peptide-hormone-therapies-for-health-performance-longevity">hubermanlab.com</a>.<h2>Thank you to our sponsors</h2>AG1: <a href="https://drinkag1.com/huberman">https://drinkag1.com/huberman</a>Joovv: <a href="https://joovv.com/huberman">https://joovv.com/huberman</a>BetterHelp: <a href="https://betterhelp.com/huberman">https://betterhelp.com/huberman</a>Function: <a href="https://functionhealth.com/huberman">https://functionhealth.com/huberman</a>Eight Sleep: <a href="https://eightsleep.com/huberman">https://eightsleep.com/huberman</a><h2>Timestamps</h2>00:00:00 Dr. Craig Koniver00:04:52 Sponsors: Joovv &amp; BetterHelp00:07:40 What is a Peptide?00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation00:18:43 BPC-157, Inflammation00:23:27 BPC-157, Injection &amp; Oral Forms; Injury Repair00:28:43 Sourcing, Anabolic Steroids, Testosterone00:34:48 Black &amp; Gray Market, Compounding Pharmacies, Purity00:38:20 Sponsor: AG100:39:51 Partnering with a Physician, LPS00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects &amp; Doses00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep &amp; Growth Hormone00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides00:58:45 Sponsor: Function &amp; Eight Sleep01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health01:05:16 Prescriptions, Physicians &amp; Trust01:14:09 Agency in Your Health01:17:13 MK-677, Appetite01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing01:21:10 Methylated B Vitamins, Homocysteine01:24:47 Peptides for Sleep, Pinealon, Epitalon01:31:03 Glycine, Liver Detoxification; Dosage01:37:19 GLP-1, Compounding Pharmacies01:39:03 Stem Cell Therapy, PRP01:41:18 Thymosin Alpha-1, Cerebrolysin &amp; Brain Health01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses01:50:20 Covid, NAD Infusion, NMN &amp; NR Supplements01:57:13 Nutritional Deficiencies; NAD Dose &amp; Regimen, NMN &amp; NR02:07:53 PT-141, Vyleesi, Libido; Nausea02:10:57 FDA Approval &amp; Removal, Pharmaceutical Companies02:20:17 Positivity, Mindset &amp; Health02:26:23 Zero-Cost Support, YouTube, Spotify &amp; Apple Follow &amp; Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter<a href="https://www.hubermanlab.com/disclaimer">Disclaimer &amp; Disclosures</a>

Huberman Lab discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.

Huberman Lab

In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance.